ID   S3C8L0_OPHP1            Unreviewed;       525 AA.
AC   S3C8L0;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Carbonic anhydrase {ECO:0000313|EMBL:EPE09839.1};
GN   ORFNames=F503_07615 {ECO:0000313|EMBL:EPE09839.1};
OS   Ophiostoma piceae (strain UAMH 11346) (Sap stain fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Ophiostoma.
OX   NCBI_TaxID=1262450 {ECO:0000313|EMBL:EPE09839.1, ECO:0000313|Proteomes:UP000016923};
RN   [1] {ECO:0000313|EMBL:EPE09839.1, ECO:0000313|Proteomes:UP000016923}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 11346 {ECO:0000313|EMBL:EPE09839.1,
RC   ECO:0000313|Proteomes:UP000016923};
RX   PubMed=23725015; DOI=10.1186/1471-2164-14-373;
RA   Haridas S., Wang Y., Lim L., Massoumi Alamouti S., Jackman S., Docking R.,
RA   Robertson G., Birol I., Bohlmann J., Breuil C.;
RT   "The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and
RT   a comparison with the bark beetle-associated pine pathogen Grosmannia
RT   clavigera.";
RL   BMC Genomics 14:373-373(2013).
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DR   EMBL; KE148147; EPE09839.1; -; Genomic_DNA.
DR   AlphaFoldDB; S3C8L0; -.
DR   STRING; 1262450.S3C8L0; -.
DR   VEuPathDB; FungiDB:F503_07615; -.
DR   eggNOG; KOG0382; Eukaryota.
DR   HOGENOM; CLU_039326_0_1_1; -.
DR   OrthoDB; 49814at2759; -.
DR   Proteomes; UP000016923; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd03124; alpha_CA_prokaryotic_like; 1.
DR   Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 2.
DR   InterPro; IPR041891; Alpha_CA_prokaryot-like.
DR   InterPro; IPR001148; CA_dom.
DR   InterPro; IPR036398; CA_dom_sf.
DR   InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR   PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR   PANTHER; PTHR18952:SF266; CARBONIC ANHYDRASE 2, ISOFORM A; 1.
DR   Pfam; PF00194; Carb_anhydrase; 2.
DR   SMART; SM01057; Carb_anhydrase; 1.
DR   SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR   PROSITE; PS51144; ALPHA_CA_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016923};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        54..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          157..518
FT                   /note="Alpha-carbonic anhydrase"
FT                   /evidence="ECO:0000259|PROSITE:PS51144"
SQ   SEQUENCE   525 AA;  54573 MW;  224E3531EC3F0B43 CRC64;
     MQSPFLGLVD VELTRLHVQQ LPCDRRMATE SSYDCVLICI KYVPMSSYRS KCDILSFLLS
     SWSGSCFFSL VSFAYSVIFD SPRAGRDLFY KLYIASFNRL PFFFFLFFFS LAVLFTMLHI
     NSYLLLIASF AAEHAYASCA YGTHLHARAE EGGVKVNTFG YTGSISPLNW LSLDPAANTA
     CATGRNQSPI DMTEGQFSLI SAADVALNIP DIEETEIENL GTTVEVVVPE GTNATMTSGG
     TVFSMKQFHF HLPSEHLDAG RSFAMEMHMV FESADGKIAV LGNYLDTANG PNVVAGVKGG
     SAGNASAAAK RSHARDILSE RQVQVVRLGT DGATATPAST SSTQSVIDKL LQLLGGGLAG
     NAAGSATGGT TSEKIEATKG AAGGATGGTA TGAATGAAAA VGVDTAGSAL INTVWASASQ
     VATPGTKAKI GPLVMSGLAD SIKAASLQTY AGSLTTPPCS EGVSWFVSTQ KQTVSLNTFE
     TARDIIGFNS RFPQNKLGEP NVLALAASAN NGAAAAAAAA NAAKA
//