ID S3CBY4_GLAL2 Unreviewed; 609 AA.
AC S3CBY4;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=FAD/NAD(P)-binding protein {ECO:0000313|EMBL:EPE24102.1};
GN ORFNames=GLAREA_07952 {ECO:0000313|EMBL:EPE24102.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE24102.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE24102.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; KE145373; EPE24102.1; -; Genomic_DNA.
DR RefSeq; XP_008088190.1; XM_008089999.1.
DR AlphaFoldDB; S3CBY4; -.
DR GeneID; 19467003; -.
DR KEGG; glz:GLAREA_07952; -.
DR eggNOG; KOG1238; Eukaryota.
DR HOGENOM; CLU_002865_6_2_1; -.
DR OMA; FPNHEWH; -.
DR OrthoDB; 858083at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR PANTHER; PTHR11552:SF210; GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000137-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT DOMAIN 9..315
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 453..594
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
FT BINDING 94
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 234
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 609 AA; 67268 MW; 7190EB7560A968DF CRC64;
MSSSADDLYD FILVGAGSAS CLITSRLSQQ LPDHRILVLE AGEHIRNDPK VQTPGLAHTL
QSNPIYDWQY STGLEPGLNE RSIKHPRGKL VGGTSAINSH SIVFPNYEWH DRLAKGLLTD
AGVNDWSSEG MKECYARWQD ENSQTKANHD EESPDRVQTS FPRSIDFLQS QWMRVFEDFG
HTAVATGFTE SSVGPVMVTN AIDASKGERS HAGTAFLEPA LKRGNVTLRT GVKVDKIVFD
KVLTGGKLNA TGVRYTHQGE EHFISGREIV LCAGVFESPL ILERSGVGSK EVLAAADVPV
LYELPGVGEN LQDHLNCSLS FETHDDVPTR DNVYRDPEVQ KAALLEYEQS RTGRLSEGAA
YSFAFTPLQM LETQSETQQL TEMVRHLVEE TSSPSLQAQY AFIQKTSENP HEATATTFML
RTQRNRDTDS LPKGTPSIVP GNYVTVVAML AHPFSRGSCH ISSDLSIGPV INFNYLSHPL
DTEILARHLR LIERLFQQPT FLAMAKPGGR RLPRSFPHPI SSLEDAKKIL PINSATNYHP
CGTCSMMKEE LRGVVDERLK VYGTNNIRVC DASVLPIIPR GNILTAVYAF AEKAAEIICR
ETKASCQSD
//
