ID S3D1L2_GLAL2 Unreviewed; 877 AA.
AC S3D1L2;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=p-loop containing nucleoside triphosphate hydrolase {ECO:0000313|EMBL:EPE31054.1};
GN ORFNames=GLAREA_04021 {ECO:0000313|EMBL:EPE31054.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE31054.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE31054.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KE145363; EPE31054.1; -; Genomic_DNA.
DR RefSeq; XP_008082465.1; XM_008084274.1.
DR AlphaFoldDB; S3D1L2; -.
DR STRING; 1116229.S3D1L2; -.
DR GeneID; 19463076; -.
DR KEGG; glz:GLAREA_04021; -.
DR eggNOG; KOG0385; Eukaryota.
DR HOGENOM; CLU_000315_17_3_1; -.
DR OMA; PNIFTDW; -.
DR OrthoDB; 5482994at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR10799:SF923; PASG; 1.
DR PANTHER; PTHR10799; SNF2/RAD54 HELICASE FAMILY; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EPE31054.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT DOMAIN 153..327
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 634..801
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..87
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..466
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..493
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 877 AA; 99048 MW; C7FDDBA0ED8CE563 CRC64;
MRSSEAGTRS PSPASRLPTS TPSSPPDLRD EDELEPEFLS KEDQLLYEEE RAARAANEKA
EAKKRAAALK KKKKQEESKE EREKKSMKLE ELLKKSEAFS ARLTGKTQCL GRVGSSVDGK
SLGEHNLTMA KQPKCMVGGT MRDYQLEGLT WMVEICSQGM SGILADEMGL GKTIQTISLI
AHLREVEDYL GPHLIIAPLS TLSNWIEEFQ KWTPDVPVLL YHGTQAHRRE IFKSQIMKHV
GKGGRPTKRF PVVCTSPEMV LRDFNDLTKI MWEFIIIDEG HRMKNNESKL FQVLKTFTSA
SRLLITGTPL QNNMKELWSL LNFLLPTIFI HWEQFEEWFD FSDLQDEEGT AQFIADKQNK
ELLRKMRVVL QPLLLRRIKA DVEHLLPKKR EYILYAPMTK DQTELYNAIT DKKTDTRKFL
EDKILERLTA TAGASNGSSV KAEASDDDGS DDEKPLALRP RPKAETKTAP KNAFQQMMQK
KSATSSRASS KGSLKRKSPA DVETPVPKSA KSSRHSTPAT SVRRTKTRGR KVYKEADASD
EDELSDDEFE QKLVEEAAEL EKKNNVREVA GTKEELELAK MVELAKKEVS GKKLGNPIMQ
LRLICNSVHN FYNPWATGLP VDESLVTSSG KMLLLDRLLK ALFERGHKVL VFSQFKVQLD
LLEDYARDLR KWNVCRIDGS VAQDDRRLQI KEFNENPEFR LFLLSTRAGG QGINLASADT
VILFDSDWNP QQDLQAQDRA HRIGQKNPVV IFRLATKNTV EEGLLSSAEG KRRLEKAVIK
KTEFGKGPMT DDTKMQLELK QLLLKDGMVF TGTGKNKEEI LSDKDLDILC DRSDAAYERA
AKGLGDTENF KVIETKYDGI ASMMGNEEAE ASLPVEA
//
