ID S3D6L4_GLAL2 Unreviewed; 547 AA.
AC S3D6L4;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=S-adenosyl-L-methionine-dependent methyltransferase {ECO:0000313|EMBL:EPE34137.1};
GN ORFNames=GLAREA_07150 {ECO:0000313|EMBL:EPE34137.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE34137.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE34137.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
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DR EMBL; KE145357; EPE34137.1; -; Genomic_DNA.
DR RefSeq; XP_008079289.1; XM_008081098.1.
DR AlphaFoldDB; S3D6L4; -.
DR STRING; 1116229.S3D6L4; -.
DR GeneID; 19466203; -.
DR KEGG; glz:GLAREA_07150; -.
DR eggNOG; KOG1499; Eukaryota.
DR HOGENOM; CLU_017375_6_0_1; -.
DR OMA; DGWAVWF; -.
DR OrthoDB; 197898at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR049482; ANM3-like_C2H2_Zf.
DR InterPro; IPR025799; Arg_MeTrfase.
DR InterPro; IPR041698; Methyltransf_25.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR PANTHER; PTHR11006; PROTEIN ARGININE N-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11006:SF116; PROTEIN METHYLTRANSFERASE; 1.
DR Pfam; PF21137; ANM3_C2H2_Zf; 1.
DR Pfam; PF13649; Methyltransf_25; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51678; SAM_MT_PRMT; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01015}; Reference proteome {ECO:0000313|Proteomes:UP000016922};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01015}.
FT DOMAIN 69..113
FT /note="Protein arginine N-methyltransferase 3-like C2H2
FT zinc finger"
FT /evidence="ECO:0000259|Pfam:PF21137"
FT DOMAIN 247..344
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13649"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 185..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..34
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 547 AA; 61751 MW; 2B1370BC7CBCB9D9 CRC64;
MEKEAPGSSG SSDASDILDM RDEEGWEDAE PDVEESQFIS LMDDEVFTDM MQMLDHCKAK
HNLDFLEIRS RLGLDFYGNI KLVNYLRSQV HSGKPIPSEI TKKDFDDEKY LKPVLEDDAV
LFTLDDLPEV VEIHDEVNVQ DKGKGVERDS GSLIARVSEL EEELRKVHSQ FSDYRDTVKT
TLDKKWEEPS ANGSAAPKEE PRDDDSHYFS SYSYNDIHET MLKDAVRTDA YRDFIYSNKA
LFAGKTVLDV GCGTGILSMF CAKAGAARVI AVDNSAIIDK ARENIFNNGF ADTITCLRGK
VEEVKLPVDK VDIIVSEWMG YCLLYEAMLD SVIWARDKYL QPDGLMVPSH MNMWVAPIAD
PDYISDHIAF WRDVYGFDMK AMQAGIHEDA QVLDMPASTL AADPFPFLQL SLHTTAVKDL
VFKRKWSGKL KKDIDALDGF IIWFDSFFIP SRTEVVAEDA KAEEWAASGK SGNAFTTGPG
GKVTHWKQGV MLIDNTKEKP VGHKEGEQLS GELEYAVPED NSRALNVSLT WKFESWQKEN
SQSWKMR
//
