ID S3DA42_GLAL2 Unreviewed; 697 AA.
AC S3DA42;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Class II aaRS and biotin synthetase {ECO:0000313|EMBL:EPE35297.1};
GN ORFNames=GLAREA_10996 {ECO:0000313|EMBL:EPE35297.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE35297.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE35297.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC Type 1 subfamily. {ECO:0000256|ARBA:ARBA00006303}.
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DR EMBL; KE145354; EPE35297.1; -; Genomic_DNA.
DR RefSeq; XP_008077376.1; XM_008079185.1.
DR AlphaFoldDB; S3DA42; -.
DR STRING; 1116229.S3DA42; -.
DR GeneID; 19470038; -.
DR KEGG; glz:GLAREA_10996; -.
DR eggNOG; KOG2411; Eukaryota.
DR HOGENOM; CLU_014330_2_1_1; -.
DR OMA; YQLDVEM; -.
DR OrthoDB; 1046261at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006418; P:tRNA aminoacylation for protein translation; IEA:InterPro.
DR Gene3D; 3.30.1360.30; GAD-like domain; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR HAMAP; MF_00044; Asp_tRNA_synth_type1; 1.
DR InterPro; IPR004364; Aa-tRNA-synt_II.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004524; Asp-tRNA-ligase_1.
DR InterPro; IPR002312; Asp/Asn-tRNA-synth_IIb.
DR InterPro; IPR004115; GAD-like_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR00459; aspS_bact; 1.
DR PANTHER; PTHR22594:SF5; ASPARTATE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR22594; ASPARTYL/LYSYL-TRNA SYNTHETASE; 1.
DR Pfam; PF00152; tRNA-synt_2; 1.
DR PRINTS; PR01042; TRNASYNTHASP.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT DOMAIN 224..681
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 697 AA; 77683 MW; 102ABCB4E6B77FB7 CRC64;
MIATSYAKRN ISCLNPRGLT RLSSWHKTAR LPASANASRR CFHDGKDVAP RRNTNIAESE
YLKEYKGAYN VSTNASFFDF ESITDHLNTE TVAAGFLVST RRLSDSLLFA TLRKGIGKDV
QILVRDPEMV KKVGSTNLYS AVSVTGTLQL KRQPKNKAEG SKEGPATAKD VELVAEEFVC
LNSFSEDIPS GPDRVHPPTS RHLQIRFDPK LQAAILFRSE VLKFARKGLA DFTEVETPIL
FKSTPEGARE FLVPTRRAGR AYALPQSPQQ YKQILMASGI EKYVQFARCF RDEDLRSDRQ
PEFTQIDLEM AWTDGEGVMK RVEQFVKDLY CNVTHPAFSL PSLDQAPFYR MDYDEAMTEH
GSDKPDLRIP GLIHRIDHIV PKQLLGMITH LENPIIEAYK IRLDGTPQTI QTFLRDFFKT
TEGQIFDQNP HGVPGISIYD PRKPLEGLQT FGFEGAELIK DFYGSLPKGR LDSEEEHKIA
STLDEGDLLL LQARSDLSHS GGSTPLGDLR RAIYQAAVSR GLLKADPRHL YLWVTGFPMF
TPENGVDPGQ GGRSKFSATH HPFTAPKTAA DVDLLISNPL KAKADHYDLV VNGVELGGGS
RRIHSAEMQK FVMRDVLKMR DERINDFDHL LKSLAAGCPP HAGFAFGFDR LMAVLCGTDS
VRDVIAFPKN GSGDDLMVGS PGKIGSDDLK PYHLKRD
//
