ID S3DCB5_GLAL2 Unreviewed; 590 AA.
AC S3DCB5;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=RNA-binding, RBD {ECO:0000313|EMBL:EPE24283.1};
GN ORFNames=GLAREA_08134 {ECO:0000313|EMBL:EPE24283.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE24283.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE24283.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE145373; EPE24283.1; -; Genomic_DNA.
DR RefSeq; XP_008088371.1; XM_008090180.1.
DR AlphaFoldDB; S3DCB5; -.
DR STRING; 1116229.S3DCB5; -.
DR GeneID; 19467184; -.
DR KEGG; glz:GLAREA_08134; -.
DR eggNOG; KOG0154; Eukaryota.
DR HOGENOM; CLU_012131_1_1_1; -.
DR OMA; SLKLMYW; -.
DR OrthoDB; 1947879at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR PANTHER; PTHR13948:SF3; FI21118P1; 1.
DR PANTHER; PTHR13948; RNA-BINDING PROTEIN; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF00076; RRM_1; 2.
DR Pfam; PF00641; zf-RanBP; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00547; ZnF_RBZ; 1.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50102; RRM; 2.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}; Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 1..76
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 84..117
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 152..266
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 508..554
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT REGION 181..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 64754 MW; CB8403FA43F9176B CRC64;
MNELQHKLRL DGLEEIRIIK DKKTGKSRQF AFAQFATIAD ATRLLERHYP SLTLYDPQEG
AQQGTSQPVK VRIAYSRERD DRDKAGYGED DWKCDVCYLP NFSSRTLCFR CNAPRTRASA
HGIVIAQANM SAFSGFATTG DSDAALDGNA SQFLLLRGLE PGVNEDLLAK GVSKLYKTKA
TNSSNDNQAN KKTKIASTSN DSSYGAKEGS LRRVLLIRDR KTNDSWRYGF AEFSTVEDAQ
AAVAKYKASE KFTISSKPVM ISYIHAGVFV PVLRPLENGD AQFTFSPLSN NAIKLMYWDE
AAYANELVTA VAEQPSVEKR KQSEHAKRAA AAANEGLVDQ SKEGEARPKK RKVEKEAKIV
APHLQFWSNR HAEIHGITPK QPEDAIPGAS QNSVDNKILT DGTKPSTQSF ADLNRKCCLL
CSRQFKSEED VKKHEHTSKL HRDNMKDSAL VANALSKLSK SIENPNSSAY RDRAKERRQA
FNQPKQPAAQ HNRGSKPSTD TDAIDTSVQS KGAALLGKMG WTAGEGLGAQ GTGMTDAIRT
DLYSAGVGLG AQGGKLGDAA EEAQRQTTGT YADFLNKTKD KAKERFESLA
//
