ID S3DE76_GLAL2 Unreviewed; 491 AA.
AC S3DE76;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=MFS general substrate transporter {ECO:0000313|EMBL:EPE36717.1};
GN ORFNames=GLAREA_08880 {ECO:0000313|EMBL:EPE36717.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE36717.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE36717.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KE145352; EPE36717.1; -; Genomic_DNA.
DR RefSeq; XP_008076032.1; XM_008077841.1.
DR AlphaFoldDB; S3DE76; -.
DR GeneID; 19467928; -.
DR KEGG; glz:GLAREA_08880; -.
DR eggNOG; KOG0255; Eukaryota.
DR HOGENOM; CLU_008455_1_1_1; -.
DR OMA; YKYGEWL; -.
DR OrthoDB; 3672446at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17323; MFS_Tpo1_MDR_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23502; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23502:SF135; MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16320)-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..483
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 491 AA; 53198 MW; 93F98A959FDB8D40 CRC64;
MEKEGSSSHQ ASRLEAGSLE HNDLVDPNIV DWSGPDDVED PHNWSSSRRW AQIILVSLFA
LVTNMAPTIC APAIEQIISE FQIASQNVST LAITIYLLGL AVGPMFMSPL SEVYGRQPVL
LVANLLFVCF IVGCALSQDV GEFMIFRFLS GCAGGTPMTL GGGTIADVTR MDKRAVAMAL
FSLGPLTGPV LGPVIGGPIA ASIGWRWSFW LMSILGGAVG IASLVLGRET SPKILLERKA
ACLRASSGNK NLRSKLAHHL TPQEVLFQAL FKPLMLLVRS PVLLIISLYV ALVFGLMYLL
FTTFPEVFEG QYGFGTATSG LVYLGLGVAL VVCMLIFKAF NMRVQETCMK RDGVQQPKAE
YRLVLMMFFS PFVGVGLFIY GWSTLYKVHW IVPIIGTSLI GVGAFFVLMP AQLYLVDLFG
SGAAASALGA NNILRYLSST FLPLAGPAMY KALGYGWGNT LLGFLSLCFV PAPILFYKYG
ESLRTRTPVK V
//
