ID   S3DRC8_GLAL2            Unreviewed;       356 AA.
AC   S3DRC8;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=NAD(P)-linked oxidoreductase {ECO:0000313|EMBL:EPE29028.1};
GN   ORFNames=GLAREA_00186 {ECO:0000313|EMBL:EPE29028.1};
OS   Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Helotiaceae; Glarea.
OX   NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE29028.1, ECO:0000313|Proteomes:UP000016922};
RN   [1] {ECO:0000313|EMBL:EPE29028.1, ECO:0000313|Proteomes:UP000016922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX   PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA   Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA   Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT   "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT   the fungus Glarea lozoyensis.";
RL   BMC Genomics 14:339-339(2013).
CC   -!- SIMILARITY: Belongs to the aldo/keto reductase family.
CC       {ECO:0000256|ARBA:ARBA00007905}.
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DR   EMBL; KE145367; EPE29028.1; -; Genomic_DNA.
DR   RefSeq; XP_008083137.1; XM_008084946.1.
DR   AlphaFoldDB; S3DRC8; -.
DR   GeneID; 19459246; -.
DR   KEGG; glz:GLAREA_00186; -.
DR   eggNOG; KOG1575; Eukaryota.
DR   HOGENOM; CLU_023205_2_0_1; -.
DR   OMA; FMPQRFD; -.
DR   OrthoDB; 5357470at2759; -.
DR   Proteomes; UP000016922; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd19079; AKR_EcYajO-like; 1.
DR   Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43364; NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED; 1.
DR   PANTHER; PTHR43364:SF9; OXIDOREDUCTASE; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT   DOMAIN          35..347
FT                   /note="NADP-dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00248"
SQ   SEQUENCE   356 AA;  39753 MW;  9C3B840BD8C823E2 CRC64;
     MSTPQMPKSL AASVEGSKAE YVRLGKSGLK ISVPVFGTMS IGDPGWIDWV EGEEKSLPLL
     KAAYDMGLNT WDTANVYSNG ASEILVGKAI KKYNIPRNKV VVLTKCFGAV GEEMGVRSVM
     FPKEIKASKD YVNNHGLSRA AIFNAVDASL KRLELDYIDL LQIHRFDPDT PHEETMEALH
     DLIKSGKVRY IGASSMWATQ FAQLQFVAEK NGWTKFISMQ NHYSLLYREE EREMNRFCND
     TGVGLIPWAP LFRGHLARPL SNLGKTTRSA PEADKGLTEA DEGIVKRVQE LADKKGWKMS
     HVALAWINKR VSSPIIGFSS VERIQEALDA RGKTLTDEEE KYLEELYAPK NIIGHS
//