ID   S3WZU7_9ACTN            Unreviewed;       741 AA.
AC   S3WZU7;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=UvrD-like helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51198};
GN   ORFNames=HMPREF1531_01910 {ECO:0000313|EMBL:EPH02602.1};
OS   Propionibacterium sp. oral taxon 192 str. F0372.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Propionibacteriaceae; Propionibacterium.
OX   NCBI_TaxID=1203605 {ECO:0000313|EMBL:EPH02602.1, ECO:0000313|Proteomes:UP000014567};
RN   [1] {ECO:0000313|EMBL:EPH02602.1, ECO:0000313|Proteomes:UP000014567}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0372 {ECO:0000313|EMBL:EPH02602.1,
RC   ECO:0000313|Proteomes:UP000014567};
RG   The Broad Institute Genomics Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Kirega A., Socransky S.S.,
RA   Dewhirst F.E., Izard J., Walker B., Young S., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Propionibacterium sp. oral taxon 192 str. F0372.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPH02602.1}.
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DR   EMBL; ATFL01000014; EPH02602.1; -; Genomic_DNA.
DR   RefSeq; WP_016669698.1; NZ_KE340297.1.
DR   AlphaFoldDB; S3WZU7; -.
DR   STRING; 1203605.HMPREF1531_01910; -.
DR   PATRIC; fig|1203605.3.peg.1972; -.
DR   eggNOG; COG3973; Bacteria.
DR   HOGENOM; CLU_010312_3_1_11; -.
DR   Proteomes; UP000014567; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF13245; AAA_19; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000014567}.
FT   DOMAIN          194..591
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         215..222
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   741 AA;  81964 MW;  C74E883DF98EC9DB CRC64;
     MNQSNDSQAE LIAREIAVEQ AHVDAVYRSL ELATESARSI QAESHRKYRT DRSDWMREED
     GTAMFERDAF AFQAAKRLAT LDAQHEGLVF GRLDFVDQEK RYVGRIGVRD ADYEPLVIDW
     RAPAAEAFYR ATAANPMEVV RRRVLRCHDD KVTGIEDDLL NDQASSNLVV IGEGALMASL
     QRARGHRMRD IVATIQAEQD EAIRAPYQGV TIISGGPGTG KTVVALHRAA FLLYTHRRRL
     EQGGVLVVGP TDLFMSYIER VLPGLGEDSV TLKSIGELGT DVLGFSSQLV DDAEAAVIKG
     SLRMLKVLRR AVNEPLTAES MRLRVSVKGE VLTLNPAELT RLRRDILASH KANRAREAVG
     KGLLDALWAH LSPDIAATLD IDRSYFDDTI TSQGAYTMFL NAWWPTLSPE QVLARLADPA
     MAHKFGHDVL DEAERQVLTD SLAHARGYVP GSGSPRPAWT VADIALLDEL AHMIGPTPVE
     ADADPTLFLT DGSQVSELVT LADQLTTRRE IETEDETVII HSHVLVDESQ DVTPMQWRML
     RRRGPQASWT LVGDPAQSSY PSNEETRRAM RDLVGRGASR TFTLTTNYRS PAEIMELAGR
     VVRREYPSAQ VPTSVRTTGI KPLLDVITPQ QLAASLREHL TTLTSQVDGT IAVICAGHRI
     EEMREMIVAL DLPTALAGRL EVRTALQVKG LEFDAVIVVD PDDIVAHTSG GMRVLYVALT
     RPTQRLVTLD LTPDPVWRRN L
//