ID   S3ZMR2_9ACTN            Unreviewed;       296 AA.
AC   S3ZMR2;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Putative oxidoreductase GLYR1 like protein {ECO:0000313|EMBL:EPH44831.1};
GN   ORFNames=STRAU_2121 {ECO:0000313|EMBL:EPH44831.1};
OS   Streptomyces aurantiacus JA 4570.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
OX   NCBI_TaxID=1286094 {ECO:0000313|EMBL:EPH44831.1, ECO:0000313|Proteomes:UP000014629};
RN   [1] {ECO:0000313|EMBL:EPH44831.1, ECO:0000313|Proteomes:UP000014629}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JA 4570 {ECO:0000313|EMBL:EPH44831.1,
RC   ECO:0000313|Proteomes:UP000014629};
RA   Gruening B.A., Praeg A., Erxleben A., Guenther S., Mueller M.;
RT   "Draft Genome Sequence of Streptomyces aurantiacus, Which Produces
RT   Setomimycin.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HIBADH-related family.
CC       {ECO:0000256|ARBA:ARBA00009080}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPH44831.1}.
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DR   EMBL; AOPZ01000074; EPH44831.1; -; Genomic_DNA.
DR   AlphaFoldDB; S3ZMR2; -.
DR   PATRIC; fig|1286094.4.peg.2098; -.
DR   Proteomes; UP000014629; Unassembled WGS sequence.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR015815; HIBADH-related.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR048666; RedAm-like_C.
DR   PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   Pfam; PF21761; RedAm-like_C; 1.
DR   PIRSF; PIRSF000103; HIBADH; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014629}.
FT   DOMAIN          13..161
FT                   /note="6-phosphogluconate dehydrogenase NADP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03446"
FT   DOMAIN          168..294
FT                   /note="NADPH-dependent reductive aminase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21761"
SQ   SEQUENCE   296 AA;  30324 MW;  3C405C570E2AB1E4 CRC64;
     MPATDFSPAA HPVSVFGLGM MGSALAAALL KAGHPTTVWN RTVAKTGPLV AQGATPAETP
     AAGVAASPLV IACLTTNDNV RELFAPLAAE LRGRTLVNLT NGTPSQAREL AAWAQEHGIA
     YIDGGIMAVP QMIAGPGAYI LYSGDEAAYA THRETLAALA DTKWVGTDAG LAALWDLALL
     TGMYGMGIGV AQAYALIGSA GVPAKDFAPL LTDWVIAMTQ GIVPGTAEAI DSGQHLTDVS
     SLEVNQAAVP NLATTFAEHG VRDLLFGAMQ PLLDRAVAEG YGADGLSRLV DLLKTP
//