ID S4H0D7_GARVA Unreviewed; 302 AA.
AC S4H0D7;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=CRISPR-associated endonuclease Cas1, NMENI subtype {ECO:0000313|EMBL:EPI56716.1};
GN ORFNames=HMPREF1573_00731 {ECO:0000313|EMBL:EPI56716.1};
OS Gardnerella vaginalis JCP7276.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Gardnerella.
OX NCBI_TaxID=1261058 {ECO:0000313|EMBL:EPI56716.1, ECO:0000313|Proteomes:UP000014591};
RN [1] {ECO:0000313|EMBL:EPI56716.1, ECO:0000313|Proteomes:UP000014591}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCP7276 {ECO:0000313|EMBL:EPI56716.1,
RC ECO:0000313|Proteomes:UP000014591};
RA Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA Pepin K.H., Bhonagiri V., Zhang X., Warren W., Mitreva M., Mardis E.R.,
RA Wilson R.K.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer, forms a heterotetramer with a Cas2 homodimer.
CC {ECO:0000256|ARBA:ARBA00038592}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPI56716.1}.
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DR EMBL; ATJR01000025; EPI56716.1; -; Genomic_DNA.
DR RefSeq; WP_020760588.1; NZ_KE348469.1.
DR AlphaFoldDB; S4H0D7; -.
DR PATRIC; fig|1261058.4.peg.665; -.
DR HOGENOM; CLU_055263_0_0_11; -.
DR Proteomes; UP000014591; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004520; F:DNA endonuclease activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR GO; GO:0043571; P:maintenance of CRISPR repeat elements; IEA:InterPro.
DR Gene3D; 1.20.120.920; CRISPR-associated endonuclease Cas1, C-terminal domain; 1.
DR InterPro; IPR002729; CRISPR-assoc_Cas1.
DR InterPro; IPR042206; CRISPR-assoc_Cas1_C.
DR InterPro; IPR019855; CRISPR-assoc_Cas1_NMENI.
DR NCBIfam; TIGR00287; cas1; 1.
DR NCBIfam; TIGR03639; cas1_NMENI; 1.
DR PANTHER; PTHR34353; CRISPR-ASSOCIATED ENDONUCLEASE CAS1 1; 1.
DR PANTHER; PTHR34353:SF2; CRISPR-ASSOCIATED ENDONUCLEASE CAS1 1; 1.
DR Pfam; PF01867; Cas_Cas1; 1.
PE 4: Predicted;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000313|EMBL:EPI56716.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722}.
SQ SEQUENCE 302 AA; 33914 MW; F7D89FC1ACC1F907 CRC64;
MQNAWRVIDC TNLQGELRYI RGRILVCDHA LEQKVEIPLA ETAILLIGLH CNCSAGLLHQ
CAEYGTCVMT CDWRCVPISA MHSWVNVPTR ITIRQLSQAT MSVPRRKAAW AQIVRAKIRG
QAACLDLLNK EGGGLLRGLS NTVRSGDVTN REGQAAREYW KRIFPKEEDF HRKPGSGQDR
NALLDYAYMV LRGFSIRAVL SAGLNPTMGM NHHNGTNYFC LADDIIEPFR PAVDYAVSKL
SFYDTPNDKA VKKYLIDSVN QQFNGSGHTI PSALSDLAQS YGIYVEKDME EFQVPQFVRS
EL
//
