ID S4HLB0_GARVA Unreviewed; 445 AA.
AC S4HLB0;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Phosphoribosylglycinamide formyltransferase 2 {ECO:0000313|EMBL:EPI58090.1};
GN ORFNames=HMPREF1572_00052 {ECO:0000313|EMBL:EPI58090.1};
OS Gardnerella vaginalis JCP7275.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Gardnerella.
OX NCBI_TaxID=1261057 {ECO:0000313|EMBL:EPI58090.1, ECO:0000313|Proteomes:UP000014557};
RN [1] {ECO:0000313|EMBL:EPI58090.1, ECO:0000313|Proteomes:UP000014557}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCP7275 {ECO:0000313|EMBL:EPI58090.1,
RC ECO:0000313|Proteomes:UP000014557};
RA Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA Pepin K.H., Bhonagiri V., Zhang X., Warren W., Mitreva M., Mardis E.R.,
RA Wilson R.K.;
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Purine metabolism. {ECO:0000256|ARBA:ARBA00025704}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPI58090.1}.
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DR EMBL; ATJS01000003; EPI58090.1; -; Genomic_DNA.
DR RefSeq; WP_020761482.1; NZ_KE348649.1.
DR AlphaFoldDB; S4HLB0; -.
DR PATRIC; fig|1261057.4.peg.50; -.
DR HOGENOM; CLU_011534_1_3_11; -.
DR Proteomes; UP000014557; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR003135; ATP-grasp_carboxylate-amine.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR048740; PurT_C.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR PANTHER; PTHR43055; FORMATE-DEPENDENT PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; 1.
DR PANTHER; PTHR43055:SF1; FORMATE-DEPENDENT PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; 1.
DR Pfam; PF02222; ATP-grasp; 1.
DR Pfam; PF21244; PurT_C; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Purine biosynthesis {ECO:0000256|ARBA:ARBA00022755};
KW Transferase {ECO:0000313|EMBL:EPI58090.1}.
FT DOMAIN 140..350
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
SQ SEQUENCE 445 AA; 48793 MW; 60E722B4ECE07E29 CRC64;
MSFSQKSDSN NELNESVTNE RIFGIFDSKL HTTKVLLLGS GELGKEIAIE LIRLGIRVCA
ADSYANAPAM QVAQENRVLD MSDSQELQDL INDINPDIII PEIEAISTQI LKNVVKSKKI
QVVPSSDITA IAMDREALRK ISHEKLGLPT TPYRFASNYE ELEKGAKIVG YPCVVKPIMS
SSGHGQSIVK NPENLQNAWV EAQNGRRSKH KNQNAQNADI SRVIVEALAP LDYELTVLTV
SSSAGITTCE PIAQFQKNGD YRQSWQPANI PENVRINAQN IAKRVVEGLS QIARENGETG
WGVYGVELFV LKNGDLLFNE LSPRPHDTGM VTMISQYYSE FALHVLAILG VPITQKHTAL
CLKNNEVALS HALVVEGNGK IGFANVAKSL NTEDCARCDI RIFGKPEVHG SRRLGVILTV
SNSVRDAKSC ATRIASELHT VELPS
//
