ID S4NBI1_9PORP Unreviewed; 757 AA.
AC S4NBI1;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Cell division protein FtsI {ECO:0000313|EMBL:GAD04842.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:GAD04842.1};
GN ORFNames=PORCRE_539 {ECO:0000313|EMBL:GAD04842.1};
OS Porphyromonas crevioricanis JCM 15906.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Porphyromonas.
OX NCBI_TaxID=1305617 {ECO:0000313|EMBL:GAD04842.1, ECO:0000313|Proteomes:UP000018031};
RN [1] {ECO:0000313|Proteomes:UP000018031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15906 {ECO:0000313|Proteomes:UP000018031};
RA Sakamoto M., Tanaka N., Shiwa Y., Yoshikawa H., Ohkuma M.;
RT "Draft Genome Sequences of Porphyromonas crevioricanis JCM 15906T and
RT Porphyromonas cansulci JCM 13913T Isolated from a Canine Oral Cavity.";
RL Genome Announc.1:e00483-13(2013).
RN [2] {ECO:0000313|EMBL:GAD04842.1, ECO:0000313|Proteomes:UP000018031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15906 {ECO:0000313|EMBL:GAD04842.1,
RC ECO:0000313|Proteomes:UP000018031};
RA Sakamoto M., Tanaka N., Shiwa Y., Yoshikawa H., Ohkuma M.;
RT "Draft Genome Sequences of Porphyromonas crevioricanis JCM 15906T and
RT Porphyromonas cansulci JCM 13913T Isolated from a Canine Oral Cavity.";
RL Genome Announc. 1:e00483-13(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD04842.1}.
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DR EMBL; BAOU01000013; GAD04842.1; -; Genomic_DNA.
DR RefSeq; WP_023936645.1; NZ_BAOU01000013.1.
DR AlphaFoldDB; S4NBI1; -.
DR Proteomes; UP000018031; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.10.20; -; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR PROSITE; PS51178; PASTA; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000313|EMBL:GAD04842.1};
KW Cell division {ECO:0000313|EMBL:GAD04842.1};
KW Glycosyltransferase {ECO:0000313|EMBL:GAD04842.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:GAD04842.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 678..733
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT REGION 734..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 738..757
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 83448 MW; DCB11246D083FFFF CRC64;
MARKLNSRPE LNSSARYRLW GGVMVIAVLV VLWRVLVTMY QDGEEWRHIG ESLHRPQEEN
IYPYRGTIYS ADGEELAITA PHYRLYMDFQ AEAFKQLDHK SAMLLLDSLS LVLSEKLSTP
EELIKASYLK AQWIKGYKKK SRSCLLVNKD ISYLDVKEMY AAPPFRDKEN HSNRALTHSI
VKVDRAKRIN PYGSLGRRTI GSVYAEVTGG LTRGKGGLEL AFDSLLRGEL GKVLRLYNAG
RVTLNTIREP KPGANVHSTL DMRKQAIVEH ELRSSLELAE AESGTAVLME VATGKILAIS
NLGRLKSGAY AETQNFAVSD LSEPGSTFKT VSMLIALDQG LCTPEDTVDV GNGIWQVGNR
RLMDWTVGKR AGLGRISYAE AMHQSSNVGI AKLIQKNFKD RPKAYVQSVR KMGLCDNFDL
DIPGAAKHAI VRFPEEGAYW SATTLPWMAH GYETQIPPIS TLAFYNAIAN GGRFMKPYFV
NKVVSPNGEI LIENSPTVLH ESIASEQAIM QIKDILRGVV TSGTAKRGAL SDKVALCGKT
GTAVLGNARS GYSERNYQIS FAGFFPYEAP KYSMIVVVRK PHVPEYRSAG ISCGGVMKRV
AETIMSIESR LPIDSMHIAS GMKIPHIQSG KRDVVLASLS TAGLSERMTK KPPKTRFVQV
KQSGKQIELH STRPYSRGVV PDLVGMSPSD AVYALAGCGF RSVLHGFGPV FSQSIPAGSR
AAIGQKVHLY LTHRSTMSGS KEESKLQSEQ KNKTKKE
//
