ID S4PMP8_9NEOP Unreviewed; 211 AA.
AC S4PMP8;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Kinetochore protein SPC25 {ECO:0000256|RuleBase:RU367150};
OS Pararge aegeria (speckled wood butterfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Satyrinae; Satyrini; Parargina; Pararge.
OX NCBI_TaxID=116150 {ECO:0000313|EMBL:JAA89120.1};
RN [1] {ECO:0000313|EMBL:JAA89120.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Ovary {ECO:0000313|EMBL:JAA89120.1};
RX PubMed=23622113; DOI=10.1186/1471-2164-14-283;
RA Carter J.M., Baker S.C., Pink R., Carter D.R., Collins A., Tomlin J.,
RA Gibbs M., Breuker C.J.;
RT "Unscrambling butterfly oogenesis.";
RL BMC Genomics 14:283-283(2013).
RN [2] {ECO:0000313|EMBL:JAA89120.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Ovary {ECO:0000313|EMBL:JAA89120.1};
RA Carter J.-M., Baker S.C., Pink R., Carter D.R.F., Collins A., Tomlin J.,
RA Gibbs M., Breuker C.J.;
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a component of the essential kinetochore-associated
CC NDC80 complex, which is required for chromosome segregation and spindle
CC checkpoint activity. {ECO:0000256|RuleBase:RU367150}.
CC -!- SUBUNIT: Component of the NDC80 complex.
CC {ECO:0000256|RuleBase:RU367150}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU367150}.
CC Chromosome, centromere, kinetochore {ECO:0000256|RuleBase:RU367150}.
CC -!- SIMILARITY: Belongs to the SPC25 family.
CC {ECO:0000256|ARBA:ARBA00006379, ECO:0000256|RuleBase:RU367150}.
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DR EMBL; GAIX01003440; JAA89120.1; -; Transcribed_RNA.
DR AlphaFoldDB; S4PMP8; -.
DR OrthoDB; 3234578at2759; -.
DR GO; GO:0031262; C:Ndc80 complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0007059; P:chromosome segregation; IEA:InterPro.
DR Gene3D; 3.30.457.50; Chromosome segregation protein Spc25; 1.
DR InterPro; IPR013255; Spc25_C.
DR Pfam; PF08234; Spindle_Spc25; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|RuleBase:RU367150};
KW Cell division {ECO:0000256|RuleBase:RU367150};
KW Centromere {ECO:0000256|RuleBase:RU367150};
KW Chromosome {ECO:0000256|RuleBase:RU367150};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Kinetochore {ECO:0000256|RuleBase:RU367150};
KW Mitosis {ECO:0000256|RuleBase:RU367150};
KW Nucleus {ECO:0000256|RuleBase:RU367150}.
FT DOMAIN 151..202
FT /note="Chromosome segregation protein Spc25 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08234"
FT COILED 55..110
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 211 AA; 25223 MW; 49C8B4EE277E7315 CRC64;
MGVIDENWNY EFDIEATEKS SNIAFELKIN DLCESVLKAF DYGFVNIVVD KDCLARNKDE
EFKLLIEKNK ELKHEIEIKL KDLSQQQSQY ENFKRDQKLL EQEIKETHEA FLMGRKQYKK
CLNIYYSIES KSNEMQVVFI QFFTELKKIG ESYSIYLLRN SKTHQYTLQS MNPTLRIFKE
LQRKLQETND VPGVLCWIRQ AFISHKLNKN H
//
