ID S4R4Y8_PETMA Unreviewed; 334 AA.
AC S4R4Y8;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=DNA fragmentation factor, beta polypeptide (caspase-activated DNase) {ECO:0000313|Ensembl:ENSPMAP00000000268.1};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000000268.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000000268.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; S4R4Y8; -.
DR STRING; 7757.ENSPMAP00000000268; -.
DR Ensembl; ENSPMAT00000000268.1; ENSPMAP00000000268.1; ENSPMAG00000000239.1.
DR GeneTree; ENSGT00390000014490; -.
DR HOGENOM; CLU_049235_1_1_1; -.
DR OMA; KAEHVEW; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0004520; F:DNA endonuclease activity; IEA:InterPro.
DR GO; GO:0006309; P:apoptotic DNA fragmentation; IEA:InterPro.
DR Gene3D; 3.10.20.10; -; 1.
DR InterPro; IPR003508; CIDE-N_dom.
DR InterPro; IPR039729; DFF40.
DR InterPro; IPR015311; DFF40_C.
DR InterPro; IPR044925; His-Me_finger_sf.
DR PANTHER; PTHR13067; CASPASE-ACTIVATED DNASE; 1.
DR PANTHER; PTHR13067:SF2; CASPASE-ACTIVATED DNASE; 1.
DR Pfam; PF02017; CIDE-N; 1.
DR Pfam; PF09230; DFF40; 1.
DR SMART; SM00266; CAD; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF54060; His-Me finger endonucleases; 1.
DR PROSITE; PS51135; CIDE_N; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|PROSITE-ProRule:PRU00447};
KW Reference proteome {ECO:0000313|Proteomes:UP000245300}.
FT DOMAIN 6..86
FT /note="CIDE-N"
FT /evidence="ECO:0000259|PROSITE:PS51135"
SQ SEQUENCE 334 AA; 39689 MW; 7193511B1142FA33 CRC64;
AMEGESPRMF RVRVPSDAQR FGVVAVSLCQ LVTKAAIKLK LAERSVGPLR VCLEEDGTEV
VDEEYFSVLD RNTCLVILKR NERWTGVGVH AVSHAMVHFE RCTRDVLEIF RKDPNGKYRN
ILKNFLNSIE DCSERESRQD DPKWFEGVDN RFKHKREEMR YRCKTRMRGY LSKELHGFFF
QTVSNVKYCS EYRWLRELLR NELKTERFNE DYFDRSAAVV VRLCDNNGQF SCQGAYNKQD
CQYQHKINPY ANWESRIQFS VWNLDHRIEK SREVLPSLKS ALEKSNGRQI NWRYFYGLLF
TRENLKLVDI VCHDKTCHKL KCKKLKFYVQ KCVN
//
