ID S4REY1_PETMA Unreviewed; 254 AA.
AC S4REY1;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=CTCK domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000003763.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000003763.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00039}.
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DR AlphaFoldDB; S4REY1; -.
DR STRING; 7757.ENSPMAP00000003763; -.
DR Ensembl; ENSPMAT00000003779.1; ENSPMAP00000003763.1; ENSPMAG00000003452.1.
DR HOGENOM; CLU_961651_0_0_1; -.
DR OMA; TIDAKEC; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR006207; Cys_knot_C.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR006208; Glyco_hormone_CN.
DR InterPro; IPR001007; VWF_dom.
DR Pfam; PF00007; Cys_knot; 1.
DR Pfam; PF00093; VWC; 1.
DR SMART; SM00041; CT; 1.
DR SMART; SM00214; VWC; 2.
DR SUPFAM; SSF57603; FnI-like domain; 2.
DR PROSITE; PS01185; CTCK_1; 1.
DR PROSITE; PS01225; CTCK_2; 1.
DR PROSITE; PS01208; VWFC_1; 1.
DR PROSITE; PS50184; VWFC_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00039}; Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 17..83
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 85..153
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 152..251
FT /note="CTCK"
FT /evidence="ECO:0000259|PROSITE:PS01225"
FT DISULFID 178..227
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00039"
FT DISULFID 189..243
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00039"
FT DISULFID 193..245
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00039"
SQ SEQUENCE 254 AA; 27048 MW; 10F8DE3FFEC5DE7A CRC64;
DYQDTCNCTI RTCVSDEFCT YDGIQYQFGD TWKDGLCTDC SCVMASEGGP SKYEVLCQHT
SCPNCLPGES YIPVEGQCCG TCVRTSCVAD DGTTYEVGQI WSLDTKGCSR CECVLAGGYA
YVQCAVTQCP PVDPSCPLDL ISYSANGCCQ FCNRGSPRSG GRRVSRCNAT PWMSADGCLS
RDSVNVTGCE GACSSRSVLD AATNVYTKQC SCCSATETVT VEVEMVCPDG SARIDRFEMV
AACKCDASQC GANN
//
