ID S4RFZ6_PETMA Unreviewed; 530 AA.
AC S4RFZ6;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=RNA-binding region (RNP1, RRM) containing 3 {ECO:0000313|Ensembl:ENSPMAP00000004128.1};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000004128.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000004128.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; S4RFZ6; -.
DR STRING; 7757.ENSPMAP00000004128; -.
DR Ensembl; ENSPMAT00000004145.1; ENSPMAP00000004128.1; ENSPMAG00000003778.1.
DR GeneTree; ENSGT00530000063786; -.
DR HOGENOM; CLU_039888_2_1_1; -.
DR OMA; CPFGPIT; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12238; RRM1_RBM40_like; 1.
DR CDD; cd12239; RRM2_RBM40_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 6.10.250.610; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034147; RBM40_RRM1.
DR InterPro; IPR045164; RBM41/RNPC3.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR16105:SF0; RRM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR16105; UNCHARACTERIZED; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 8..83
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 422..505
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 87..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..226
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..246
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 530 AA; 57990 MW; 1A98FA7C6B819930 CRC64;
LSMARDRRTL LVRRLPRALP ADEGRQLLRH FGASDVRIMG PAGKMRNAAF ATFPSEAAAA
KALRRLHQLE VLGSVLAVEF ARGQDAASAR EPLPSAPGET TKHIPGSHAE SAPVLSKTSQ
LDAIAPKLGV TYPANPLLRY RYPPPTTNIL ANICHALSSS PRFLCLQVLH LMNKMNLPAP
FGHVTSPAPL VADFAPVPPA ALPQLPPLPP EEPPRDAERF PPAPPEPEPE EVEMEVSSDE
ESEYESEEDE HARRLKTMTD TAPALPKRPL GKKKISKRKR PKLKDLLVAP KAPVPGYSSQ
PALTPAQVFE QPALAVSRKI AISLPSLDPL GEREGKEERE GMEDVGMGAG EEGQGGGGFG
KMFPAPACPS PNRTDDEGEE EEEEEQPSQF ISRKELSSGR VSREEMAKSS VFKNYSAGEP
TCRLYVKNLS RQVSEQDLKH IFGRYVDFSS DVEKNMFDVR LMREGRMKGQ AFVGLPSERE
AQKALRDAHG YVLHGRPLVI QYARSARPKE ELKVGKKKSS LDAATSNHPG
//
