ID S4RL71_PETMA Unreviewed; 547 AA.
AC S4RL71;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Insulin like growth factor 2 mRNA binding protein 3 {ECO:0000313|Ensembl:ENSPMAP00000005957.1};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000005957.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000005957.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RRM IMP/VICKZ family.
CC {ECO:0000256|ARBA:ARBA00009094}.
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DR AlphaFoldDB; S4RL71; -.
DR SMR; S4RL71; -.
DR STRING; 7757.ENSPMAP00000005957; -.
DR Ensembl; ENSPMAT00000005985.1; ENSPMAP00000005957.1; ENSPMAG00000005383.1.
DR GeneTree; ENSGT00940000154957; -.
DR HOGENOM; CLU_020744_1_0_1; -.
DR OMA; PTINARY; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.310.210; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR10288:SF337; IGF-II MRNA-BINDING PROTEIN, ISOFORM L; 1.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR Pfam; PF00013; KH_1; 4.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00322; KH; 4.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 4.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50084; KH_TYPE_1; 4.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 41..116
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 117..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 547 AA; 61113 MW; A95C2E9220974FC3 CRC64;
FCTAPFDFWA KVALEVFLGK AEIQGSTIEI EHSVPRWQRY RKIQVRDIPS SLQWEELLSI
LAECGSVESC NRVNSEGSST VVNVVFSTKE QAEIALDMLN NKEVSSRQLK ASYIPDEEVP
NQSPREAGDN RMMRNPKRGG YFPRQDAPRP GSPQDCGCSL TMRRPDIPVR ILVPAQFLGA
VFGKEGATIK KITQDSRSKI DVQRKEWSGS AEKVVTIHSS EEGSIEACRL ILDIVRDEAK
STNFAGEIPL KLLVHNDFVG RIIGREGRNL KRIEQESGTK ITISRLQDLS MYNPERTISL
DGSTEQCMKA EAEIVKQVWE MCDRDAESAQ MEANFIPGMN LGMVGLFPPS GSMPNSPRQV
SGSPASACWC MQGEQETVFL LIPAQAVGTM IGRQGQHIQQ LARFAGANIK IAPAETPESK
ERMVIITGHP EAQFKAQGRI FRKLKEENFV PPREEVRLEV RIKVPTAAAG RVIGRGGRTV
TELQNLTCAE VLVPRDQTPD EDDYIFVKIV GHFFASQMAQ RKIREIVARL KQRPSPLRQG
KQQQEQD
//
