ID S4S814_HPV16 Unreviewed; 178 AA.
AC S4S814;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Helicase {ECO:0000313|EMBL:AFJ19577.1};
DE Flags: Fragment;
GN Name=E1 {ECO:0000313|EMBL:AFJ19577.1};
OS Human papillomavirus type 16.
OC Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes;
OC Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae;
OC Alphapapillomavirus; Alphapapillomavirus 9.
OX NCBI_TaxID=333760 {ECO:0000313|EMBL:AFJ19577.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1] {ECO:0000313|EMBL:AFJ19577.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATT12 533 C2 {ECO:0000313|EMBL:AFJ19577.1};
RX PubMed=23881083; DOI=10.1007/s00705-013-1790-8;
RA Tsakogiannis D., Darmis F., Gortsilas P., Ruether I.G., Kyriakopoulou Z.,
RA Dimitriou T.G., Amoutzias G., Markoulatos P.;
RT "Nucleotide polymorphisms of the human papillomavirus 16 E1 gene.";
RL Arch. Virol. 159:51-63(2014).
CC -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000256|ARBA:ARBA00004147}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JQ791023; AFJ19577.1; -; Genomic_DNA.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.510; Zinc finger, large T-antigen D1 domain; 1.
DR InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001177; PPV_DNA_helicase_E1_C.
DR InterPro; IPR037102; Znf_lg_T-Ag_D1_dom_sf.
DR Pfam; PF00519; PPV_E1_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51206; SF3_HELICASE_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AFJ19577.1};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Early protein {ECO:0000256|ARBA:ARBA00022518};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:AFJ19577.1};
KW Host nucleus {ECO:0000256|ARBA:ARBA00022562};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 89..178
FT /note="SF3 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51206"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFJ19577.1"
FT NON_TER 178
FT /evidence="ECO:0000313|EMBL:AFJ19577.1"
SQ SEQUENCE 178 AA; 20389 MW; FA2F66F8C04493C8 CRC64;
WAYDNDIVDD SEIAYKYAQL ADTNSNASAF LKSNSQAKIV KDCATMCRHY KRAEKKQMSM
SQWIKYRCDR VDDGGDWKQI VMFLRYQGVE FMSFLTALKR FLQGIPKKNC ILLYGAANTG
KSLFGMSLMK FLQGSVICFV NSKSHFWLQP LADAKIGMLD DATVPCWNYI DDNLRNAL
//
