ID S4UZL2_PLAVI Unreviewed; 402 AA.
AC S4UZL2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Merozoite surface protein 1 {ECO:0000256|ARBA:ARBA00022062};
DE AltName: Full=Merozoite surface antigen {ECO:0000256|ARBA:ARBA00031689};
DE AltName: Full=PMMSA {ECO:0000256|ARBA:ARBA00032276};
DE Flags: Fragment;
OS Plasmodium vivax (malaria parasite P. vivax).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5855 {ECO:0000313|EMBL:AGN53470.1};
RN [1] {ECO:0000313|EMBL:AGN53470.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Myanmar_99 {ECO:0000313|EMBL:AGN53470.1};
RA Zhou X., Chen J.-H.;
RT "Genetic diversity in C-terminal region of Plasmodium vivax merozoite
RT surface protein 1 of imported cases from Myanmar in Yunnan province, P.R.
RT China.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004609};
CC Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}. Membrane
CC {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor
CC {ECO:0000256|ARBA:ARBA00004589}.
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DR EMBL; JX490145; AGN53470.1; -; Genomic_DNA.
DR AlphaFoldDB; S4UZL2; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR010901; MSP1_C.
DR InterPro; IPR024730; MSP1_EGF_1.
DR Pfam; PF12947; EGF_3; 1.
DR Pfam; PF12946; EGF_MSP1_1; 1.
DR Pfam; PF07462; MSP1_C; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Merozoite {ECO:0000313|EMBL:AGN53470.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 373..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..227
FT /note="Merozoite surface 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07462"
FT DOMAIN 297..333
FT /note="Merozoite surface protein EGF"
FT /evidence="ECO:0000259|Pfam:PF12946"
FT DOMAIN 340..379
FT /note="EGF"
FT /evidence="ECO:0000259|Pfam:PF12947"
FT COILED 140..167
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AGN53470.1"
SQ SEQUENCE 402 AA; 45640 MW; 14F7B1591CC46F28 CRC64;
DQVTTGEAES EAPEILVPAG ISDYDVVYLK PLAGMYKTIK KQLENHVNAF NTNITDMLDS
RLKKRNYFLE VLNSDLNPFK YSSSGEYIIK DPYKLLDLEK KKKLIGSYKY IGASIDMDVA
TANDGVAYYN KMGELYKTHL DGVKTEIKKV EDDIKKQDEE LKKLGNVNSQ DSKKNEFIAK
KAELEKYLPF LNSLQKEYES LVSKVNTYTD NLKKVISNCQ LEKKEAEITV KKLQDYNKMD
EKLEEYKKSE KKNEVKSSGL LEKLMKSKLI KENESKEILS QLLNVQTQLL TMSSEHTCID
TNVPDNAACY RYLDGTEEWR CLLTFKEEGG KCVPASNVTC KDNNGGCAPE AECKMTDSNK
IVCKCTKEGS EPLFEGVFCS SSSFLSLSFL LLMLLFLLCM EL
//
