ID   S4UZN9_PLAVI            Unreviewed;       402 AA.
AC   S4UZN9;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Merozoite surface protein 1 {ECO:0000256|ARBA:ARBA00022062};
DE   AltName: Full=Merozoite surface antigen {ECO:0000256|ARBA:ARBA00031689};
DE   AltName: Full=PMMSA {ECO:0000256|ARBA:ARBA00032276};
DE   Flags: Fragment;
OS   Plasmodium vivax (malaria parasite P. vivax).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=5855 {ECO:0000313|EMBL:AGN53466.1};
RN   [1] {ECO:0000313|EMBL:AGN53466.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Myanmar_75 {ECO:0000313|EMBL:AGN53466.1};
RA   Zhou X., Chen J.-H.;
RT   "Genetic diversity in C-terminal region of Plasmodium vivax merozoite
RT   surface protein 1 of imported cases from Myanmar in Yunnan province, P.R.
RT   China.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004609};
CC       Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor
CC       {ECO:0000256|ARBA:ARBA00004589}.
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DR   EMBL; JX490141; AGN53466.1; -; Genomic_DNA.
DR   AlphaFoldDB; S4UZN9; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.10.25.10; Laminin; 2.
DR   InterPro; IPR024731; EGF_dom.
DR   InterPro; IPR010901; MSP1_C.
DR   InterPro; IPR024730; MSP1_EGF_1.
DR   Pfam; PF12947; EGF_3; 1.
DR   Pfam; PF12946; EGF_MSP1_1; 1.
DR   Pfam; PF07462; MSP1_C; 1.
DR   SUPFAM; SSF57196; EGF/Laminin; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Merozoite {ECO:0000313|EMBL:AGN53466.1};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        373..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..227
FT                   /note="Merozoite surface 1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07462"
FT   DOMAIN          297..333
FT                   /note="Merozoite surface protein EGF"
FT                   /evidence="ECO:0000259|Pfam:PF12946"
FT   DOMAIN          340..379
FT                   /note="EGF"
FT                   /evidence="ECO:0000259|Pfam:PF12947"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AGN53466.1"
SQ   SEQUENCE   402 AA;  45580 MW;  C39C47C3D40E8F14 CRC64;
     DQVTTGEAES EAPEILVPAG ISDYYVVYLK PLAGMYKTIK KQLENHVNAF NTNITDMLDS
     RLKKRNYFLE VLNSDLNPFK YSSSGEYIIK DPYKLLDLEK KKKLIGSYKY IGASIDMDLA
     TANDGVAYYN KMEELYKTHL TAVNEEVKKV EADIKAEDDK IKKIGSDSTK TTEKTQSMAK
     KAELEKYLPF LNSLQKEYES LVSKVNTYTD NLKKVISNCQ LEKKEAEITV KKLQDYNKMD
     EKLEEYKKSE KKNEVKSSGL LEKLMKSKLI KENESKEILS QLLNVQTQLL TMSSEHTCID
     TNVPDNAACY RYLDGTEEWR CLLTFKEEGG KCVPASNVTC KDNNGGCAPE AECKMTDSNK
     IVCKCTKEGS EPLFEGVFCS SSSFLSLSFL LLMLLFLLCM EL
//