ID S4VCL5_HORVS Unreviewed; 895 AA.
AC S4VCL5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=RGA1 {ECO:0000313|EMBL:AGO59117.1};
GN Name=Rga1 {ECO:0000313|EMBL:AGO59117.1};
OS Hordeum vulgare subsp. spontaneum (Wild barley) (Hordeum spontaneum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX NCBI_TaxID=77009 {ECO:0000313|EMBL:AGO59117.1};
RN [1] {ECO:0000313|EMBL:AGO59117.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23841622; DOI=10.1094/PHYTO-01-13-0030-R;
RA Arora D., Gross T., Brueggeman R.;
RT "Allele characterization of genes required for rpg4-mediated wheat stem
RT rust resistance identifies Rpg5 as the R gene.";
RL Phytopathology 103:1153-1161(2013).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KC433591; AGO59117.1; -; Genomic_DNA.
DR AlphaFoldDB; S4VCL5; -.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1123; NB-ARC DOMAIN CONTAINING PROTEIN, EXPRESSED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614}.
FT DOMAIN 12..87
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 137..284
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 895 AA; 99823 MW; 7FA02265FD5B2086 CRC64;
MEVAVVVGPI VKLLPKLLSV IDGKRKQLDS LEVDAGFIRR DLQSIQEIIG RSNGSRSITD
LWVRDLRRLA DDMEDCIDRF QVGKMSRISF VGKICKLKKR SKETLEQLQN CISIAGAAAP
APDPPSAPGG TDQDPEEQLL GLLARSQPEG NLKVISVAGF SGVGMTRLAH KVYSDRDVRS
QFPLHAWVRA APGMSVLKLL QKIHDQLMLI SITKDHGETA SNSKIIPQIN GNAQHAVSDH
PLAGLLKTGR YLIVIDGVNT HELYDVLSAF SWADGMDGRI IMTTTIQLPA ATCCKCGNGS
SLAMDSTSQV FIGELTESGF VESCLHLRDD TLARMRRSSK EILSSPVVQD LLLYFCMFPR
DHPVRRNPLI RRWLAEGLVF PQPETEIFSQ DVAVKNLESL ISRNIIQPIQ VRTYGNVKKC
QTSGIMLNSI SSKSKSQNFI TMLCGGQTTE KNLPGKEIRR LSLHLNGAAN GPLDLPKQLS
RLHTLAVFPD DTNITRHQAN LNYAEYKLLR VLDLKECADV KAEHVGKICD LLLLKYLSLG
DSIDKVPRKI VKLKWLETLD MRRTQVVMLP IEVLHLPGLK HLLGKFQLLE GDCTQKKLEK
LLSEDSELQR LSGFVTDKSE GFAQLMGRMV KLRKVKIWCD SSADVTKLDH VLGAMKKFIR
EGLDMTRVDR SLSMDFQGCP TECSERFMDS LQATGRLTSL KLRGKLTQLP QFQAKLNYIE
ELCLSRTNLS GDTILDGLSE LRMTLKYLKL VEDKLEHLVI KPEHFRSLKG LCLVGEQRMQ
DITIQDEAMP YLVSLHILCE ALGNLPGVDI THMKRLKEVA LHSGVEEMIK DGWQTAAMNH
PNRPNVLFIH HANSSPRDSP PCQATVEIAN RTKPIGRKFT ASIMGGIFAC ARPRS
//
