ID S4XUM2_SORCE Unreviewed; 1669 AA.
AC S4XUM2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AGP35590.1};
GN ORFNames=SCE1572_14260 {ECO:0000313|EMBL:AGP35590.1};
OS Sorangium cellulosum So0157-2.
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=1254432 {ECO:0000313|EMBL:AGP35590.1, ECO:0000313|Proteomes:UP000014803};
RN [1] {ECO:0000313|EMBL:AGP35590.1, ECO:0000313|Proteomes:UP000014803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So0157-2 {ECO:0000313|EMBL:AGP35590.1,
RC ECO:0000313|Proteomes:UP000014803};
RX PubMed=23812535; DOI=10.1038/srep02101;
RA Han K., Li Z.F., Peng R., Zhu L.P., Zhou T., Wang L.G., Li S.G.,
RA Zhang X.B., Hu W., Wu Z.H., Qin N., Li Y.Z.;
RT "Extraordinary expansion of a Sorangium cellulosum genome from an alkaline
RT milieu.";
RL Sci. Rep. 3:2101-2101(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR EMBL; CP003969; AGP35590.1; -; Genomic_DNA.
DR RefSeq; WP_020734818.1; NC_021658.1.
DR STRING; 1254432.SCE1572_14260; -.
DR KEGG; scu:SCE1572_14260; -.
DR PATRIC; fig|1254432.3.peg.3208; -.
DR eggNOG; COG0515; Bacteria.
DR eggNOG; COG1366; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG3899; Bacteria.
DR HOGENOM; CLU_000445_34_2_7; -.
DR OrthoDB; 134712at2; -.
DR Proteomes; UP000014803; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd07041; STAS_RsbR_RsbS_like; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF01740; STAS; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50837; NACHT; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR PROSITE; PS50801; STAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 7..270
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 322..413
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT DOMAIN 1547..1658
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT COILED 1514..1541
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1669 AA; 181801 MW; 5B99E31146C500A8 CRC64;
MLILQDYTAT EKIYEGITSV LYRGHRNADR LPVAVKLLKS EYPDPRELAK IRHEHALMRD
LRVPGIPVVI EVGKHGNGLA LIMEDSGGRS LSDMMRSQRL SLASALRIAA SVADIIDSVH
QRHVIHKDIK PHNILVDPET MQVKLIDFGI ATRLSRESQA ALAPEALEGT LAYMSPEQTG
RMNRVVDHRS DLYSLGVTLY EMLTGVLPFQ ANDAMELVHH HIARRPAPPA EVSPQLPQIV
SELVMKLLAK TAEARYQSGA GLKADLEECL SQLEATGEIQ PFALGRSDRV GELRIVQKLY
GREEQTATLL AAFDRASRGA VELLLVSGEA GVGKSALVQE LHKTIAHRRA YFIEGAFEQI
GRSTPYASVA SALRSLVRSL LAERTSALEL WKARLLEALG PNGQVLLDLV PELALVIGPQ
PAVAELGPTE SQNRFNLVFQ NFLRVFATRE HPVVLALEDL QWADAASLKL LHALMTGPGT
AHLLVVGTTR EGEIAAAHPL RLLVDALRSA SVAVHAIAVE PLPRPAVAQL VAEALDCAAE
QAAPLSEVVF DKTRGNPFFV GQFLRSLRQE DLLRFDARSR SWTWDLAPIQ AMQMTDNVVA
LMAGKLQRLA PDTQRALMLA ACLGHEFELE VLSAICDRSR RDTAGDLWEA LRDGLIQPTG
TEYRFVHASS RGDAADDVPS TRFNVSYRFL HDRVQQAAYS LLDDERRKAA HLRIGRLLLS
NAGASPRDDA LFAVVHQMNL AADLISDPGE RAELARLNLA AGRRAKAANA HQAAAGYLAA
GASLLGEEAW ARDGELMFAL TVTLAECEYM CGHFDRAESL FDLLLSRASS TLERAQVHDL
RIVLYLTLFK VADCISVGRA GLALFGIELP RSEEQVQAAL DAELAEVPVN LGGRRIEDLA
FAPALRDREA LIVLRLLTNL SSPAYLTDAR LAALVTAKQV NLSLRHGHSE VSAFGFVLYG
LYMAVLRDRY DEARRFGRLG IELNRRFDNV ELACKIHFTF GVYAHFFSPL RETVEHLRSA
FEAGMVSADF AYLSYTCNAI VMARLGLGDE LASVRKEIDR FLGLMERTKN ALSTAFLSIA
RQMVACLEGR TDGGASLSDD ELDEAELVAT LGAPSAMFTA FWYHVVKLEL LFLDEEHAAA
LSEALAAERA LASSMGYVST TELSFYLCLT LLALGEAAPE GPARGAAMLE EHHARLGRWA
ESCPENYRHK HLLVAAERSR ASGDELGAMA RYEEAIEAAQ ESGFVRDEAL ASELCAKFHL
AKGRRKTARF YLASACYGYV RWGATAKAQA LVDRYPALAL QPAVGSGRAD APVSFTASSS
STANTGRKGV LDVTAMIRAA QVIAGEVELD NVLEQLMRIA VENAGAQRGA LVLDRGERLV
VEALATVDPD AVRTGMTTPV EDSAEIAASV VQYVARTREP VVLGDATEDA RFAADPYIAA
SRPRSVLCMS MIHRGRLTGV LYLENNAVSN AFTAARIELL GLLLSQAAIA VENALLYAHL
QHRTEELRVA GERLELELAE RARSEQTRAS LQEEIIRVQN DRLAELSTPL IPITDRIMVM
PLIGTMDAAR AQQVLHTALQ GVDANSTQVV IIDITGVKSI DTGVAASLIR TANALRLLGA
QAVITGVRGD VAQTLVALDI DFGAIVTKGT LQSGIAYALE QSRRTRRLS
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