ID S4XYW8_SORCE Unreviewed; 1648 AA.
AC S4XYW8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AGP35813.1};
GN ORFNames=SCE1572_15650 {ECO:0000313|EMBL:AGP35813.1};
OS Sorangium cellulosum So0157-2.
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=1254432 {ECO:0000313|EMBL:AGP35813.1, ECO:0000313|Proteomes:UP000014803};
RN [1] {ECO:0000313|EMBL:AGP35813.1, ECO:0000313|Proteomes:UP000014803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So0157-2 {ECO:0000313|EMBL:AGP35813.1,
RC ECO:0000313|Proteomes:UP000014803};
RX PubMed=23812535; DOI=10.1038/srep02101;
RA Han K., Li Z.F., Peng R., Zhu L.P., Zhou T., Wang L.G., Li S.G.,
RA Zhang X.B., Hu W., Wu Z.H., Qin N., Li Y.Z.;
RT "Extraordinary expansion of a Sorangium cellulosum genome from an alkaline
RT milieu.";
RL Sci. Rep. 3:2101-2101(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003969; AGP35813.1; -; Genomic_DNA.
DR STRING; 1254432.SCE1572_15650; -.
DR KEGG; scu:SCE1572_15650; -.
DR PATRIC; fig|1254432.3.peg.3516; -.
DR eggNOG; COG0515; Bacteria.
DR eggNOG; COG1366; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG3899; Bacteria.
DR HOGENOM; CLU_000445_34_2_7; -.
DR Proteomes; UP000014803; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd07041; STAS_RsbR_RsbS_like; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF01740; STAS; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR PROSITE; PS50801; STAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 1..258
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1517..1628
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT COILED 1475..1512
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1648 AA; 179289 MW; 4CC3460E360AE774 CRC64;
MYDTADTVIY RAKRDADGTP VTIKVLKGEH PGQRHVAQLR HELEISRHLN IDSVVRAHRL
ESIPGGAALV MEYFPGVPLD KLARSAPLDL KVKLRIASSL AGTLAAVHGK HVIHKDVKPQ
NILVNPETWQ VKLTDLGSST RLSEETLAAE RPDLLEGTLA YMSPEQTGRM NRVIDYRTDL
YSLGVTLYEL FAGALPFQAA DPVDLMHSHI ARVATPLCER SPEIPRAVSD IVQKLMSKVA
EERYQSGTGL KADLDACLSA LEATGRIEPF ELGSRDVSSE LRLPQKLYGR DAQMAELLAA
FERARGGRCE LLLIAGGAGI GKSALVNELQ KEVAQRRGQL IEGKFDQLSR NMPHAPVAGA
LRQRVRQLLT EPAESLEQWK DKLLAAAGKN AQILVELIPE LELVIGPQPA VAELGPNEAQ
NRFNLVFQDF LRVITSAEHP VVLFLDDLQW ADSASLKLLH VVLIDPGGAY LLIIGAYRDQ
EAIAGQPLMT WLGELKAAGV PRRELLLPPL SLADVQKLVA DALAARPEQV QALAEVLNAT
SKGNPFFLSQ LLKELYAAGL VSFDPGAGRW TWDLEPIRQR WGAVNVHDLL IDKMQRLSPG
TQLVLQLAAC IGHQFDLKTL ATVRELPPAD VAADLWEALR EGLVLPLDSD YRLLHAPGGA
PAELPLSVRY RFLHDRGQQA AYSLIEDARK QEVHLRIGRL MRAQLSGEPR DEDLFKVVSH
CNIGAALIDD RAEQLELARL NLTVGKRAKA SMAHAAASEH FRTGLSLLGP RGWEEDYALS
FALHRERAES EWLSGNEKHA EASIRELLGH ARSRLERAEV YNLRILVHTM RGEFEDVLRV
GREGVALFGI DLPEPLEAIQ AAFGAALAEM PVHLAGRRVE ELADAPWVGD EEQLAALRLL
AAMIPGAYTL NPALLALIAA TQVNLSLRYG NSPAAACAYG LYCLLLAGGM GRPEEARRFQ
GVSLSLCERP AGVELQCKAY VVCGAPSHLF EPVRASVACL AKAYEAGLSS GDFSFGAYAC
LNIATILLCS GHELGVLRED LTGFLRFLQR TQDPLGAPVL VVAQQMIACL EGRTNGRRSL
SDGAFDEGAF LAGLAPAQEL PRCWYFVNML ILAVLYGDPE GALLMAARAE KHSASAMGLF
LANDIPFYVS LALLALCATA TAEERERHLA AVAEHRAKIA GWARHAPENY AHKERLIGAE
VARVLGDDAE AAELYDQAIQ GARQSQFTHQ EALAHELCAR FYLQRGRDRI ARWHMTDAYR
AYLRWGATAK AEHLAKEHEQ LLDLASLGEA QPARVVGTTV TRRGSTESFD VATVVKAMQA
VAGENVLDRL LDRLMRSVVA NAGAQRGALI LERDGKLAIV ASMRVDPDVV ETGLSIPALD
GREVAASVVQ LVARTREPVV VNDARHDSRF AADPYVAERR PRSILCLSMT HQGRSAGLLY
LENNVVQRAF TPGRVEVCGL LASQAAIALE NALLIASIRA GTEALQRSNE QLQRELELRA
ASEAERALLQ QEMLRRQTPI IPITDDVLVM PIVGAMDGER AQQVLETALT GFHSRQAKVV
ILDITGVAQV DATVADALIK TAKALQLLGA KTVLSGVRPE VARALVEQSV FLGSIVTMGT
LQSSIAYALG PNGLSGSVGR RPGASRQA
//
