ID   S5LJ94_FRAAN            Unreviewed;       349 AA.
AC   S5LJ94;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Ethylene receptor {ECO:0000313|EMBL:AGR27888.1};
DE   Flags: Fragment;
GN   Name=Etr2 {ECO:0000313|EMBL:AGR27888.1};
OS   Fragaria ananassa (Strawberry) (Fragaria chiloensis x Fragaria virginiana).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae;
OC   Fragaria.
OX   NCBI_TaxID=3747 {ECO:0000313|EMBL:AGR27888.1};
RN   [1] {ECO:0000313|EMBL:AGR27888.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Song C., Ma J., Tang X., Zhang Z., Liu Y.;
RT   "Cloning and Sequence Analysis of a DNA Encoding Ethylene Receptor Etr2
RT   from Chiyoda Strawberry.";
RL   Hua Bei Nong Xue Bao 23:46-49(2008).
RN   [2] {ECO:0000313|EMBL:AGR27888.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Song C., Ma J., Tang X., Zhang Z.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC         Evidence={ECO:0000256|ARBA:ARBA00001935};
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ethylene receptor family.
CC       {ECO:0000256|ARBA:ARBA00009842}.
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DR   EMBL; KC852067; AGR27888.1; -; Genomic_DNA.
DR   AlphaFoldDB; S5LJ94; -.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051740; F:ethylene binding; IEA:UniProt.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0010105; P:negative regulation of ethylene-activated signaling pathway; IEA:UniProt.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   PANTHER; PTHR24423:SF633; ETHYLENE RECEPTOR 2; 1.
DR   PANTHER; PTHR24423; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Ethylene signaling pathway {ECO:0000256|ARBA:ARBA00022745};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AGR27888.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          10..170
FT                   /note="GAF"
FT                   /evidence="ECO:0000259|SMART:SM00065"
FT   DOMAIN          196..261
FT                   /note="Signal transduction histidine kinase
FT                   dimerisation/phosphoacceptor"
FT                   /evidence="ECO:0000259|SMART:SM00388"
FT   COILED          166..193
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AGR27888.1"
FT   NON_TER         349
FT                   /evidence="ECO:0000313|EMBL:AGR27888.1"
SQ   SEQUENCE   349 AA;  38382 MW;  53CC12A9D633049B CRC64;
     LTQEIRKSLD RHTILSTTLF ELSETLGLQY CAVWMPNEIK TEMILTHELK GKNYSNMYNF
     SIPIGDPDVV LIKGSDGVNI LRPDSALVCG SSGDSGEPGP VAAIRMPMLR VCNFKGGTPE
     LIQTCYAILV LVLPGGEPRS WSGQELEIIK VVADQVAVAL SHAAILEESQ LMREQLAEQN
     RALQQAKMNA MMASLARNSF QKVMSDGMRR PMHSVMGLLS IMQDESLNND QRVIVDAMVR
     TSNVLSTLIN DAMDNPAKDS GRFPLEMRPF RLQPMIKEAA CLAKCLCVYR GFGFAIEVDK
     SIADHVIGDE RRVFQVILHM VGSLLNGNQG GGLVVFRVSS ENGSQGRND
//