ID S5Q530_9GOBI Unreviewed; 330 AA.
AC S5Q530;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=G protein-coupled receptor 85 {ECO:0000313|EMBL:AGR93329.1};
DE Flags: Fragment;
GN Name=gpr85 {ECO:0000313|EMBL:AGR93329.1};
OS Oxyurichthys stigmalophius (spotfin goby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Gobionellinae; Oxyurichthys.
OX NCBI_TaxID=1365571 {ECO:0000313|EMBL:AGR93329.1};
RN [1] {ECO:0000313|EMBL:AGR93329.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23911892; DOI=10.1016/j.ympev.2013.07.017;
RA Agorreta A., San Mauro D., Schliewen U., Van Tassell J.L., Kovacic M.,
RA Zardoya R., Ruber L.;
RT "Molecular phylogenetics of Gobioidei and phylogenetic placement of
RT European gobies.";
RL Mol. Phylogenet. Evol. 69:619-633(2013).
CC -!- FUNCTION: Orphan receptor. {ECO:0000256|ARBA:ARBA00035627}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KF416253; AGR93329.1; -; Genomic_DNA.
DR AlphaFoldDB; S5Q530; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR19268; G PROTEIN-COUPLED RECEPTOR; 1.
DR PANTHER; PTHR19268:SF7; G-PROTEIN COUPLED RECEPTOR 85-RELATED; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AGR93329.1};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..324
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AGR93329.1"
FT NON_TER 330
FT /evidence="ECO:0000313|EMBL:AGR93329.1"
SQ SEQUENCE 330 AA; 37120 MW; E794EDE218ADBC35 CRC64;
SPLATFLKLT SLGFIIGVGV VGNLLISILL VKDKSLHRAP YYFLLDLCAS DILRSAICFP
FVFTSVKNGS AWTYGTLTCK VIAFLGVLSC FHTAFMLFCV SVTRYLAIAH HRFYTKRLTF
WTCLAVICMV WTLSVAMAFP PVLDVGTYSF IREEDQCTFQ HRSFRANDSL GFMLLLALIL
LATQLVYLKL IFFVHDRRKM KPVQFVPAVS QNWTFHGPGA SGQAAANWLA GFGRGPTPPT
LLGIRQNSNA AGRRRLLVLD EFKTEKRISR MFYIMTFFFL ALWGPYLVAC YWRVFARGPV
VPGGYLTAAV WMSFAQAGVN PFICIFSNRE
//
