ID S5RNU8_CARRU Unreviewed; 431 AA.
AC S5RNU8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 03-MAY-2023, entry version 43.
DE SubName: Full=6-phosphogluconate dehydrogenase {ECO:0000313|EMBL:AGS06533.1};
GN ORFNames=CRDC_00225 {ECO:0000313|EMBL:AGS06533.1};
OS Candidatus Carsonella ruddii DC.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Zymobacter group; Candidatus Carsonella.
OX NCBI_TaxID=667013 {ECO:0000313|EMBL:AGS06533.1, ECO:0000313|Proteomes:UP000015332};
RN [1] {ECO:0000313|EMBL:AGS06533.1, ECO:0000313|Proteomes:UP000015332}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DC {ECO:0000313|EMBL:AGS06533.1,
RC ECO:0000313|Proteomes:UP000015332};
RX PubMed=23850282; DOI=10.1016/j.cub.2013.06.027;
RA Nakabachi A., Ueoka R., Oshima K., Teta R., Mangoni A., Gurgui M.,
RA Oldham N.J., van Echten-Deckert G., Okamura K., Yamamoto K., Inoue H.,
RA Ohkuma M., Hongoh Y., Miyagishima S.Y., Hattori M., Piel J., Fukatsu T.;
RT "Defensive bacteriome symbiont with a drastically reduced genome.";
RL Curr. Biol. 23:1478-1484(2013).
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway.
CC {ECO:0000256|ARBA:ARBA00004959}.
CC -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008419}.
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DR EMBL; CP003467; AGS06533.1; -; Genomic_DNA.
DR AlphaFoldDB; S5RNU8; -.
DR KEGG; cri:CRDC_00225; -.
DR PATRIC; fig|667013.4.peg.39; -.
DR HOGENOM; CLU_024540_4_1_6; -.
DR UniPathway; UPA00115; -.
DR Proteomes; UP000015332; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
DR GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006114; 6PGDH_C.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006183; Pgluconate_DH.
DR PANTHER; PTHR11811; 6-PHOSPHOGLUCONATE DEHYDROGENASE; 1.
DR Pfam; PF00393; 6PGD; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PRINTS; PR00076; 6PGDHDRGNASE.
DR SMART; SM01350; 6PGD; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Gluconate utilization {ECO:0000256|ARBA:ARBA00023064};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 207..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 173..427
FT /note="6-phosphogluconate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01350"
SQ SEQUENCE 431 AA; 50779 MW; A63462B787465221 CRC64;
MRNHLGIIGY GIMAKNIIIN LIKNNINISI FNKEKILLNK KIFNIILVTN CLKKFISSLP
LLKLIFLIIK TGFPIKLILF RLKKKLFKND IVIDFGNSFY KETFLNNKII NKKYNFISSG
ISGGANGALY GLCCMMDCSI KLYEKIFNTI KKIFFLKNKR YSFCLSLGLS SSHYIKMIHN
GIEYGILQLI SEIYFLLKNI IKKKKYIINV LLNWNNSIIG SYLLKILLNI LLKKKKKICD
IVDQKGTGRN FVLNSIKNNI NANSIFEALI IRIISKNIFL RKILFYNEKK LIFINKSLFL
ELTKNMFLLF KLLCYSQGLN QLIKIKKKYN WKINLNNLIK SYFDSCIIDS KILFMLINIK
KNFFLTNFFL KYIKKFFCIK KVIFFIIKCN LSSFFLISCF NLLTLLIYKN YNIKLIQFER
NYFGNHIIKY I
//
