ID S5TF29_9PROT Unreviewed; 440 AA.
AC S5TF29;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=GTPase and tRNA-U34 5-formylation enzyme {ECO:0000313|EMBL:AGS33288.1};
GN Name=mnmE {ECO:0000313|EMBL:AGS33288.1};
GN ORFNames=NASALF_160 {ECO:0000313|EMBL:AGS33288.1};
OS Candidatus Nasuia deltocephalinicola str. NAS-ALF.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nasuia.
OX NCBI_TaxID=1343077 {ECO:0000313|EMBL:AGS33288.1, ECO:0000313|Proteomes:UP000015382};
RN [1] {ECO:0000313|EMBL:AGS33288.1, ECO:0000313|Proteomes:UP000015382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAS-ALF {ECO:0000313|Proteomes:UP000015382};
RX PubMed=23918810; DOI=10.1093/gbe/evt118;
RA Bennett G.M., Moran N.A.;
RT "Small, smaller, smallest: the origins and evolution of ancient dual
RT symbioses in a Phloem-feeding insect.";
RL Genome Biol. Evol. 5:1675-1688(2013).
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DR EMBL; CP006059; AGS33288.1; -; Genomic_DNA.
DR AlphaFoldDB; S5TF29; -.
DR KEGG; ndl:NASALF_160; -.
DR PATRIC; fig|1343077.3.peg.175; -.
DR HOGENOM; CLU_019624_4_1_4; -.
DR OrthoDB; 9805918at2; -.
DR Proteomes; UP000015382; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd14858; TrmE_N; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.120.430; tRNA modification GTPase MnmE domain 2; 1.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR018948; GTP-bd_TrmE_N.
DR InterPro; IPR027368; MnmE_dom2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42714; TRNA MODIFICATION GTPASE GTPBP3; 1.
DR PANTHER; PTHR42714:SF2; TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF10396; TrmE_N; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000015382};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 291..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..127
FT /note="GTP-binding protein TrmE N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10396"
FT DOMAIN 212..316
FT /note="G"
FT /evidence="ECO:0000259|Pfam:PF01926"
SQ SEQUENCE 440 AA; 52698 MW; 9D3BAF1C157D0AD5 CRC64;
MCYKKPILNI TTKGKSAIGI IKISFGYINK KILYFIFKKI FYRKIKNKFI NYCFIYDYRN
FLIDKIIVLY FEKPNSYTGE DVIEIHCHGN YYILKFIIDN FLKILKIYSI KLSKRGEFTK
RGFLNNKIDI FELEIISNII NFKGNSFLKN IDINFKKILF SIYKLSKNLI IYFESELSKS
GKNFYYSLTY IRNKIFFILK NITLFKNNNN SIIILGFSNS GKSTFINNLS SNNLSIISSL
KGTTKNLIKK TININNLLFK VFDTPGVINF KNSIEYLNIL FVIKKKKYSK IIFYIFDSFI
FYNIFFYYIK RKIKKYQIII NILNKIDKIG KNFSLEIFIN IYIKNIKIKI SSKNGWGLNL
IKSEIKRIGF KNNYNNRNIF YKIIKKSYKN INKSYIFFLK KKYLFFKNNF YKFLKNLSLI
ILKKNKIFFN KIFKKFCLGK
//
