ID S5UZ71_STRC3 Unreviewed; 549 AA.
AC S5UZ71;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0008006|Google:ProtNLM};
GN ORFNames=B446_07200 {ECO:0000313|EMBL:AGS68264.1};
OS Streptomyces collinus (strain DSM 40733 / Tue 365).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1214242 {ECO:0000313|EMBL:AGS68264.1, ECO:0000313|Proteomes:UP000015423};
RN [1] {ECO:0000313|Proteomes:UP000015423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40733 / Tue 365 {ECO:0000313|Proteomes:UP000015423};
RA Ruckert C., Szczepanowski R., Goesmann A., Pross E.K., Musiol E.M.,
RA Blin K., Wohlleben W., Puhler A., Weber T., Kalinowski J.;
RT "The complete genome sequence of Streptomyces collinus Tu 365.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AGS68264.1, ECO:0000313|Proteomes:UP000015423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40733 / Tue 365 {ECO:0000313|Proteomes:UP000015423};
RX PubMed=24140291; DOI=10.1016/j.jbiotec.2013.10.004;
RA Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Iftime D.,
RA Musiol E.M., Blin K., Wohlleben W., Puhler A., Kalinowski J., Weber T.;
RT "Complete genome sequence of the kirromycin producer Streptomyces collinus
RT Tu 365 consisting of a linear chromosome and two linear plasmids.";
RL J. Biotechnol. 168:739-740(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP006259; AGS68264.1; -; Genomic_DNA.
DR RefSeq; WP_020938747.1; NC_021985.1.
DR AlphaFoldDB; S5UZ71; -.
DR STRING; 1214242.B446_07200; -.
DR KEGG; sci:B446_07200; -.
DR PATRIC; fig|1214242.5.peg.1493; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG2200; Bacteria.
DR HOGENOM; CLU_015702_2_1_11; -.
DR Proteomes; UP000015423; Chromosome.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Reference proteome {ECO:0000313|Proteomes:UP000015423}.
FT DOMAIN 1..224
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT DOMAIN 308..369
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 397..523
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 549 AA; 57466 MW; 76B4208AB2BC7D84 CRC64;
MHSWTDNLRF AFQPVVNLRT GAVTALEILA RPETGDVLAE ARRDPELDGR LAVLALRAAA
RKETLLPLHL NVFAATLADL GGLTPLHDAV RAAGRMPWEV TLDVVPPCIH VPHRALLEAV
ATLREQGFRI SADGIGDGDV PLRLLADLAP DLVKLDASLL ARPAVVRAMR TFCEQLGALV
AVEGVETELQ CAAALAAGAQ LAQGELFAPP ARVPVADVYV PPRSPGSLAA PRSGPPVREF
VRPAALLPVT ASAGQVRALL TGSPDVSGVL LVDQAGVPVR SVHRSRFLLS MSGRYGHALY
ADRPAFKLGD APRTVGADAT AWEVLDVVAV GGRDRTSDDV AVVDHRGRCV GVVRLADLVR
ALAETRVEEA AGLNPLTRLP GSDAITAEVD RWLAEGRTFA LSWLDIDHFK QVNDGAGFAA
GDELIRSVGR TLQAAVAGHA RVGHIGGDDF LVLAQEEVLD ALAGPVLDTP WAAGGRPVTL
SLATVVCGPG EVSDHRQAAA RLAPLKKAAK ALRGTSWVLA RAGLPGYEIR RGSGAAPAQA
GYAAAEPLG
//
