ID S5VI20_STRC3 Unreviewed; 214 AA.
AC S5VI20;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:AGS68090.1};
GN ORFNames=B446_06330 {ECO:0000313|EMBL:AGS68090.1};
OS Streptomyces collinus (strain DSM 40733 / Tue 365).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1214242 {ECO:0000313|EMBL:AGS68090.1, ECO:0000313|Proteomes:UP000015423};
RN [1] {ECO:0000313|Proteomes:UP000015423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40733 / Tue 365 {ECO:0000313|Proteomes:UP000015423};
RA Ruckert C., Szczepanowski R., Goesmann A., Pross E.K., Musiol E.M.,
RA Blin K., Wohlleben W., Puhler A., Weber T., Kalinowski J.;
RT "The complete genome sequence of Streptomyces collinus Tu 365.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AGS68090.1, ECO:0000313|Proteomes:UP000015423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40733 / Tue 365 {ECO:0000313|Proteomes:UP000015423};
RX PubMed=24140291; DOI=10.1016/j.jbiotec.2013.10.004;
RA Ruckert C., Szczepanowski R., Albersmeier A., Goesmann A., Iftime D.,
RA Musiol E.M., Blin K., Wohlleben W., Puhler A., Kalinowski J., Weber T.;
RT "Complete genome sequence of the kirromycin producer Streptomyces collinus
RT Tu 365 consisting of a linear chromosome and two linear plasmids.";
RL J. Biotechnol. 168:739-740(2013).
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DR EMBL; CP006259; AGS68090.1; -; Genomic_DNA.
DR RefSeq; WP_020938574.1; NC_021985.1.
DR AlphaFoldDB; S5VI20; -.
DR STRING; 1214242.B446_06330; -.
DR KEGG; sci:B446_06330; -.
DR PATRIC; fig|1214242.5.peg.1314; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_069356_11_1_11; -.
DR Proteomes; UP000015423; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR InterPro; IPR045823; TetR_C_32.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF160; TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)-RELATED; 1.
DR Pfam; PF19344; TetR_C_32; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000015423};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..73
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 36..55
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 214 AA; 23332 MW; 300F43E1200D7E36 CRC64;
MDTTQRTDQQ RSADRRRREL LEAADRVVLR DGPQASMNAI AAEAGITKPI LYRHFGDKGG
LYAALATRHT DALLASLRAA LDAPADRRER VEATLDTYLA AIEARPQVYR FLMHPAEGST
GGDQGFDVGK HSAPLLRRMG EELAQVIEER LDLGPGSQQL ARVWGHGIVG MMHAAGDWWL
GERPCSRAEL VRSLADLLWG RLAAAGDKVG GPGF
//
