ID S6F1G2_LACLL Unreviewed; 221 AA.
AC S6F1G2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Aspartic endopeptidase, MEROPS family A24 (Type IV prepilin peptidase family) {ECO:0000313|EMBL:CDG05478.1};
DE EC=3.4.23.43 {ECO:0000313|EMBL:CDG05478.1};
GN Name=comC {ECO:0000313|EMBL:CDG05478.1};
GN ORFNames=O9U_06375 {ECO:0000313|EMBL:CDG05478.1};
OS Lactococcus lactis subsp. lactis A12.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=1137134 {ECO:0000313|EMBL:CDG05478.1, ECO:0000313|Proteomes:UP000015361};
RN [1] {ECO:0000313|EMBL:CDG05478.1, ECO:0000313|Proteomes:UP000015361}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A12 {ECO:0000313|EMBL:CDG05478.1,
RC ECO:0000313|Proteomes:UP000015361};
RX PubMed=23872564; DOI=10.1128/AEM.01560-13;
RA Passerini D., Coddeville M., Le Bourgeois P., Loubiere P., Ritzenthaler P.,
RA Fontagne-Faucher C., Daveran-Mingot M.L., Cocaign-Bousquet M.;
RT "The Carbohydrate Metabolism Signature of Lactococcus lactis Strain A12
RT Reveals Its Sourdough Ecosystem Origin.";
RL Appl. Environ. Microbiol. 79:5844-5852(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDG05478.1}.
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DR EMBL; CBLU010000020; CDG05478.1; -; Genomic_DNA.
DR RefSeq; WP_021723103.1; NZ_CBLU010000020.1.
DR AlphaFoldDB; S6F1G2; -.
DR Proteomes; UP000015361; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-EC.
DR InterPro; IPR010627; Prepilin_pept_A24_N.
DR PANTHER; PTHR30487:SF0; PREPILIN LEADER PEPTIDASE_N-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR30487; TYPE 4 PREPILIN-LIKE PROTEINS LEADER PEPTIDE-PROCESSING ENZYME; 1.
DR Pfam; PF06750; A24_N_bact; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CDG05478.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..90
FT /note="Prepilin peptidase A24 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06750"
SQ SEQUENCE 221 AA; 25676 MW; 4E5A3FEB96424104 CRC64;
MDILFIFVIG SIFGSFFGLI VDRIPLRKSI IFGRSHCDSC QRLLAYRDLI PIFSQLSSGS
QCRYCKSKIP YLYIFLEFST ALIFVLAWVN YLNPSQFLMI ILSLILSAFD YRQHSFPFVT
WFIFALSFIL IFPLSPIFYF WLILALLAEK FNLRVGSGDF LWFFTASFSL TFLNEMLLLQ
IACSLGIIYY LITKKRAEIA FIPFLTIAYL MLLFGHQILS P
//
