ID   S6GMX1_9GAMM            Unreviewed;       325 AA.
AC   S6GMX1;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   SubName: Full=Cys regulon transcriptional activator {ECO:0000313|EMBL:EPJ47701.1};
GN   ORFNames=OFPII_11130 {ECO:0000313|EMBL:EPJ47701.1};
OS   Osedax symbiont Rs1.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Oceanospirillaceae.
OX   NCBI_TaxID=1330036 {ECO:0000313|EMBL:EPJ47701.1, ECO:0000313|Proteomes:UP000014822};
RN   [1] {ECO:0000313|EMBL:EPJ47701.1, ECO:0000313|Proteomes:UP000014822}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rs1 {ECO:0000313|Proteomes:UP000014822};
RA   Yi H., Goffredi S.;
RT   "Comparative genomics of two novel heterotrophic symbionts of deep-sea
RT   Osedax worms: functional variation and environmental selection.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPJ47701.1}.
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DR   EMBL; ASZJ01000056; EPJ47701.1; -; Genomic_DNA.
DR   AlphaFoldDB; S6GMX1; -.
DR   PATRIC; fig|1330036.3.peg.1058; -.
DR   Proteomes; UP000014822; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08413; PBP2_CysB_like; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR037423; CysB_PBP2.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR   PANTHER; PTHR30126:SF6; HTH-TYPE TRANSCRIPTIONAL REGULATOR CYSB-RELATED; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014822};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          1..57
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   325 AA;  36212 MW;  2ABB6ABCADAD9DFC CRC64;
     MKLQQLKYIL EVEKHDLNVS ATALSLFTSQ PGISKQIRLL EDELGVEVFS RSGKHLTRVT
     PAGKAILEIA GDILQKVESI KKVSQEFCDE RKGSLSIATT HTQARYALPL AITQFIQSYP
     DVSLHMQQGT PMQISEMAAN GKVDFAIATE ALSHFSDLIM MPCYRWNRSV VVPKNHPLAQ
     LSELTLEALA KYSIVTYVFG FTGRSKLDDA FKQQGLEPKV VFTAVDSDVI KTYVRLNLGV
     GIIASMAFDP DVDTDLVAID ASHLFESSTT QIGFRKGTFL RGYMYEFISL FAPHLTPDLV
     REVMNCDNRM QVDEIFAGHA LPEMN
//