ID S7MD11_MYOBR Unreviewed; 1026 AA.
AC S7MD11;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Potassium channel subfamily U member 1 {ECO:0000313|EMBL:EPQ01536.1};
GN ORFNames=D623_10030455 {ECO:0000313|EMBL:EPQ01536.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ01536.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KE161075; EPQ01536.1; -; Genomic_DNA.
DR AlphaFoldDB; S7MD11; -.
DR eggNOG; KOG1420; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0000145; C:exocyst; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006887; P:exocytosis; IEA:InterPro.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR010326; EXOC3/Sec6.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR InterPro; IPR048735; Slowpoke-like_C.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF23; POTASSIUM CHANNEL SUBFAMILY U MEMBER 1; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR Pfam; PF06046; Sec6; 1.
DR Pfam; PF21014; Slowpoke_C; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000313|EMBL:EPQ01536.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 30..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..117
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 408..503
FT /note="Ca2+-activated K+ channel Slowpoke-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21014"
SQ SEQUENCE 1026 AA; 116569 MW; 4E669BC273ADFCC1 CRC64;
MRQLCCAGNC QNPKALCLSS SSNALKFSKL LSIVFSTWFT AAGFIHLVEN SGDPWLKGRN
SQNLTYFDSI YLVMATTSTV GFGDVVAKTS LGRTFIMFFT LGSLILFANY IPEIVELFLT
KKTYTSSYEV LKGKNGLILN PPAQVMLQKN TLGFFIAESP KHVKRSFLKE DSDYLDSSGM
FYWCKATHLE KVILKRTDKS KLEFRNHIVA CIFGDAHSTL MGLQNFVMPL RASNYPRQEL
KDIVFIGSLE YMQREWRFLR NFPQIYILPG SALYTADLHA VNIEECSMCA VLSSPPMASP
QTLVDSQIIM ATLNIGSLRM SCSARTPSEA DDISPRLSES GKSWCRRIPI LTELKNPSNI
HFIEQLGGME GHLSGTSLHL STSFSTGSVF SGSFLDSLLA TAFYNYNVLE LLHMLVTGGI
SSQMEQYLDK EIVCRPSNSC FTLLSRRKRC KLGLLSLKQT ILSDIKPKKT FGQVFCGLLN
NFGILCLGLY RLIDDQEHNP EHKRGDHRKG VGRIDRSIPD QKEQTSFVPS SRSKNWKEKM
FAILDRILTR IEDTQADTME SDKMWFVCHL EIISKNILDD LIFAKNLMVK CFSPYYEVFR
NYLNMYHKAL STQIQELELE DLKANEIMSL FLWVLNTYSS TEREGNVELG LEVDMNALEI
LLSPNMVSEL LHMYMSTLTS NIIAWLWKAL ETDRKDQVEE TEPGADQTKK YKDEVQLYKE
EHLRNWQDIK VIISNYQNPE GCSSLLEELL DLKQHLNEQK PKKWLLGSNA IDIICVTMEE
YFNDFAKIKI PYKKRMMDPF VPYLEDLTLV SKSPDIRDDH VSMLLAMPGN ASWNTKQTII
EGSKPTEYYR SQPVTPIIVW IHIRSSSKEN DSSTAVTKIH EELAAFCRIY VVGHVLFLDF
QDLFHSSLTS CDFCEVETPA FMAFMFNHLL EASAGSELCF KRNCQTTESG GSLESLLIKR
KPLRLMFPST PFDVKAGLGL FGKNVTAAFQ LARVVSLNDQ FQQHNYNQGP VTSRTIALVI
KMMSGT
//
