ID S7MFA5_MYOBR Unreviewed; 837 AA.
AC S7MFA5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Zinc transporter ZIP10 {ECO:0000313|EMBL:EPQ01950.1};
GN ORFNames=D623_10009901 {ECO:0000313|EMBL:EPQ01950.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ01950.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000256|ARBA:ARBA00006939}.
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DR EMBL; KE161128; EPQ01950.1; -; Genomic_DNA.
DR RefSeq; XP_014396693.1; XM_014541207.1.
DR AlphaFoldDB; S7MFA5; -.
DR GeneID; 102251644; -.
DR KEGG; myb:102251644; -.
DR CTD; 57181; -.
DR eggNOG; KOG2693; Eukaryota.
DR OrthoDB; 5488029at2759; -.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR12191; SOLUTE CARRIER FAMILY 39; 1.
DR PANTHER; PTHR12191:SF14; ZINC TRANSPORTER ZIP10; 1.
DR Pfam; PF02535; Zip; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..837
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004542952"
FT TRANSMEM 406..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 500..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 738..759
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 765..786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 807..827
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 30..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..310
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..488
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 837 AA; 94472 MW; 5DA074648E036209 CRC64;
MKVHMHTKFC LICLLTFIFH HCNHCHEPHD HGPEEHHRHH HGLTESEASK FSELDAAKNE
KNYYIEKLFD RYGENGRLSF FGLEKLLTNL GLGEIKVVEI NHEDLGHDHV SHLDILAVQE
GKHFHSHNHQ HSHKHLNSEN QTVTSVSTKR YRKCDPEKET VEVSVKSDDK HTRDRNHRLC
HHHCLRHHLD HNTTHHFSND SITHSERGET SHEPSTETNK TQEHSESKPP KGKRKRKGKN
DENSEVITPG FPPNRDQGEQ YEHNRVHKPD RVHNPGHSHG HLPEHNGHDP GHGHQDPDPD
NEGELRHTRK REAPHVKKSA IYSAASHKDH NEDDRQHECL NVTQLLKYYG HGANSPISAD
LFTYLCPALL YQIDSRLCIE HFDKLLVEDL SKDKNTVPED KANVGASAWI CGIISVTVIS
LLSLLGVILV PIINQGCFKF LLTFLVALAV GTMSGDALLH LLPHSQGGHD HSHQHAHTHG
HGHGHSHGHE PKKFLEEYDA VLKGLVALGG IYLLFIIEHC LRMFKHYKQQ RGKQKWFMKQ
NTEESSIGRK LSDHKINNTP DADWLQLKPL AGTDDSVVSE DRLNETELTD LEGQQESPPK
NYLCVEEEKI MDHSHSDGFH TIDEHALHAA TPNHHDESKT VLRKHSHQWH HKHSHHSHGP
CHSGSDLKET GIANIAWMVI MGDGIHNFSD GLAIGAAFSA GLTGGISTSI AVFCHELPHE
LGDFAVLLKA GMTVKQAIVY NLLSAMMAYI GMFIGTAVGQ YANNITLWIF AVTAGMFLYV
ALVDMLPEML HGDGDNEEHG FCPVGQFVLQ NLGLLFGFAI MLVIALYEDK IVFDFQF
//
