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Database: UniProt
Entry: S7MIH8_MYOBR
LinkDB: S7MIH8_MYOBR
Original site: S7MIH8_MYOBR 
ID   S7MIH8_MYOBR            Unreviewed;      1313 AA.
AC   S7MIH8;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   10-MAY-2017, entry version 17.
DE   SubName: Full=Ryanodine receptor 1 {ECO:0000313|EMBL:EPQ04194.1};
GN   ORFNames=D623_10003566 {ECO:0000313|EMBL:EPQ04194.1};
OS   Myotis brandtii (Brandt's bat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Chiroptera; Microchiroptera;
OC   Vespertilionidae; Myotis.
OX   NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ04194.1, ECO:0000313|Proteomes:UP000052978};
RN   [1] {ECO:0000313|Proteomes:UP000052978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23962925; DOI=10.1038/ncomms3212;
RA   Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA   Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D.,
RA   Hee Yim S., Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N.,
RA   Chen G., Kulakova O.I., Sun Y., Lee S.G., Bronson R.T., Moskalev A.A.,
RA   Sunyaev S.R., Zhang G., Krogh A., Wang J., Gladyshev V.N.;
RT   "Genome analysis reveals insights into physiology and longevity of the
RT   Brandt's bat Myotis brandtii.";
RL   Nat. Commun. 4:2212-2212(2013).
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DR   EMBL; KE161498; EPQ04194.1; -; Genomic_DNA.
DR   Proteomes; UP000052978; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   GO; GO:0006936; P:muscle contraction; IEA:InterPro.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR033215; RyR1.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   PANTHER; PTHR13715:SF97; PTHR13715:SF97; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   Pfam; PF02026; RyR; 2.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF49899; SSF49899; 3.
DR   PROSITE; PS50188; B302_SPRY; 3.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000052978};
KW   Receptor {ECO:0000313|EMBL:EPQ04194.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT   DOMAIN      129    345       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      561    756       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      905   1118       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
SQ   SEQUENCE   1313 AA;  146025 MW;  CA679E2F84A1BF19 CRC64;
     MLSLVLNCID RLNVYTTAAH FAEFAGEEAA ESWKEIVNLL YELLASLIRG NRTNCALFSN
     NLDWLVSKLD RLEASSGILE VLYCVLIESP EVLNIIQENH IKSIISLLDK HGRNHKSKCP
     LPILTYHPWI PALVPYIMIS DLDLQVLDVL CSLCVCNGVA VRSNQDLITE NLLPGRELLL
     QTNLINYVTS IRPNIFVGRA EGSTQYGKWY FEVMVDEVTP FLTAQATHLR VGWALTEGYS
     PYPGGGEGWG GNGVGDDLYS YGFDGLHLWT GHVARPVTSP GQHLLAPEDV VSCCLDLSVP
     SISFRINGCP VQGVFEAFNL DGLFFPVVSF SAGVKVRFLL GGRHGEFKFL PPPGYAPCHE
     AVLPRERLHL EPIKEYRREG PRGPHLVGPS RCLSHTDFVP CPVDTVQIVL PPHLERIREK
     LAENIHELWA LTRIEQGWTY GPVRDDNKRL HPCLVNFHSL PEPERNYNLQ MSGETLKTLL
     ALGCHVGMAD EKAEDNLKKT KLPKTYMMSN GYKPAPLDLS HVRLTPAQTT LVDRLAENGH
     NVWARDRVAQ GWSYSAVQDI PARRNPRLVP YRLLDEATKR SNRDSLCQAV RTLLGYGYNI
     EPPDQEPSLV ESQSRWDRVR IFRAEKSYAV QSGRWYFEFE AVTTGEMRVG WARPELRPDV
     ELGADELAYV FNGHRGQRWH LGSEPFGRHW QSGDVVGCMI DLTENTIIFT LNGEILMSDS
     GSETAFRDIE IGDGFLPVCS LGPGQVGHLN LGQDVSSLRF FAICGLQEGF EPFAINMQRP
     VTTWFSKSLP QFEAVPLEHP HYEVARVDGT VDTPPCLRLT HRTWGSQNSL VEMLFLRLSL
     PVQFHQHFRC TAGATPLASP GLQPPAEDEA WAAEPDTDYE NLRRSAGRWG EAEGGKEGTA
     KEGTPGGTLQ AGAEAQPARA ENEKDATTEK NKKRGFLFKA KKAAMMTQPP ATPALPRLPR
     EVVPADNRDD PEIILNTTTY YYSVRVFAGQ EPSCVWVGWV TPDYHQHDMN FDLTKVRAVT
     VTMGDEQGNV HSSLKCSNCY MVWGGDFVSS GQQGRISHTD LVIGCLVDLA TGLMTFTANG
     KESNTFFQVE PNTKLFPAVF VLPTHQNVIQ FELGKQKNIM PLSAAMFLSE RKNPAPQCPP
     RLEVQMLMPI SWSRMPNHFL QVDTRRAGER LGWAVECQEP LIMMALHIPE ENRSGSPGCK
     LMGGGCGSGG GGLGLTQCPP TLPWDSRQHS RRPRPTLLSP DNTPGNLRSI SVGSRHTSWD
     PDATQAFPDT LQGTPDPPQE LLGPSQWTTD PPQGTIENIP RAPDPLYRAP NPS
//
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