ID S7N2D3_MYOBR Unreviewed; 1205 AA.
AC S7N2D3;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=MHC class II transactivator {ECO:0000313|EMBL:EPQ11156.1};
GN ORFNames=D623_10019170 {ECO:0000313|EMBL:EPQ11156.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ11156.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
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DR EMBL; KE163197; EPQ11156.1; -; Genomic_DNA.
DR AlphaFoldDB; S7N2D3; -.
DR eggNOG; KOG4308; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00116; LRR_RI; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR008095; MHC_II_transact.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47189; MHC CLASS II TRANSACTIVATOR; 1.
DR PANTHER; PTHR47189:SF1; MHC CLASS II TRANSACTIVATOR; 1.
DR Pfam; PF13516; LRR_6; 3.
DR Pfam; PF05729; NACHT; 1.
DR PRINTS; PR01719; MHCIIACTVATR.
DR SMART; SM00368; LRR_RI; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT DOMAIN 491..638
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REGION 339..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1205 AA; 131550 MW; 6A639CA41235C16D CRC64;
MNHFQTILTQ VRMLLSSHQR GQVQALLDNL LEEQLLSREY HCALLQEPDG EALARKISLT
LLQKGDPELA LLGWAWSGLQ GPVVERDPGY KDHGGSGQCT TMELGPLEGG YLELLNSNAD
PLQLYHLYDQ MDLAGEEEME LCSESDTDTI NCEQFSRLLC DIESDEETKE AYANIAELDQ
YVFQDSQFEG LSKDIFIEHI GLEEMISESV EMLEEAAQKS QKRPFPEELP ADLKHRKLAE
PLTAPMVTGT FLVGPVSDSS ALPCPSPAAL FNKEPTSVQT QLEETVLTPA PPSSSLLSCL
SLPAGSIHII PTLPALPQGL WQISGAGTEA SSILIYQGEM PQAPPSSSPA IPSLPKSPDR
PGSTSPFAPA AADLPSMPEP ALTSRANITE DEMSPTKCRA VRKVSSKLPK YPECVEQFCC
SLRDKYQAKP AGQEDILVEV DLMRARLERS SSKSLERELV ILDWAEQQPA REGLAGVLLA
ASDCRRPRET QVIAVLGKAG QGKSHWARAV SRAWACGQLP QYDFVFYLPC RCLDRPGDTY
RLQDLLFSLG PQPLPGDSEV FGHILRRPDR LLLILDAFEE LEAQDGLLPG TCGPMSAAEP
SSLRGLLAGL LQRKLLRGCT LLVTARSRGR LAQSLSKADA LFQMAGFSAQ QAETYVERYF
EHLGATHQQE RAVALLRGQP LLLSHSHSPT VCRAVCQLSE ALLELGEEAE LPSTLTGLYV
GLLGPAVRDS PHGALETVAR LAWELGRRHH SALREDQLPE KVRAWAVAKG LVQPCPGAPE
TELAFPSFLL QCFLAALWLA LSSEIKDKEL PQYLALTPRK KRPYDNWLEG MPRFLAGLVF
QPHARCLGAL AGPVVASVVD GKQKALTKYL KRLQPGLLQA RRLLELLHCT HEALDAGLWR
HVVQGLPANL SFLGTRLTPP DTHILGRTLE TAGRDFSLDL RRTGIDPSGL RSLVGLSCVT
QFRAALSDTV GLWESLQQHG ETKLLQAVEE KFTIEPFKAS SMKDVEDLGN LVQIQRTRSS
SEDIAGELPA IRDLKKLEFA LGPVAGPQAF PKLVRILEAF SSLQHLDLDS LSENKIGDEG
VAQLSATFPR LKALETEGKG QVTSLADGPP PSDFTCSLDS LSENKIGDEG VEQLSATFPQ
LKALETLNLS QNNITDVGAC KLAKALPSLA ASLLRLSLYN NCICDVGAKS LAHVLPDMES
LRVLE
//
