ID S7NBC8_MYOBR Unreviewed; 1931 AA.
AC S7NBC8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Myosin-7 {ECO:0000313|EMBL:EPQ13695.1};
GN ORFNames=D623_10026943 {ECO:0000313|EMBL:EPQ13695.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ13695.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril
CC {ECO:0000256|ARBA:ARBA00004657}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KE163754; EPQ13695.1; -; Genomic_DNA.
DR eggNOG; KOG0161; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd14934; MYSc_Myh16; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615:SF40; MYOSIN HEAVY CHAIN, MUSCLE-RELATED; 1.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 2.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT DOMAIN 35..84
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 88..772
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 650..672
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 833..1544
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1588..1903
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 181..188
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1931 AA; 222787 MW; 9CBF4D8916EAB73F CRC64;
MPGGYKGECG DDVDPMPFLA PPEKERLEAM SKPYDIKRSC WVKDEKEGFI AGEIQSEQGD
QVTVKTVTNQ TVTIKKDEIQ QMNPPKFYQA SDMADMTFLN EASVLDNLRQ RYTNMRIYTY
SGLFCVTVNP YRWLPIYGSR VANMYKGKKR TEMPPHLFSI SDNAYHDMLM DRENQSMLIT
GESGAGKTEN TKKVIQYFAN IGGTGKQSSD GKGSLEDQII QANPVLEAFG NAKTTRNNNS
SRFGKFIRIH FGTTGKLAGA DIESYLLEKS RVISQQAAER GYHIFYQILS NKKPELIETL
LLVPNPKEYN WMSQGVTSVE NMDDGEELLI TDVAFDVLGF SAEEKLGVYK LTGGIMHFGN
MKFKQKPREE QAEVDTTEVA DKVAHLMGLN SGELQKGITR PRVKVGNEFV QKGQNMEQCN
NSIGALGKAV YDKMFKWLVV RINKTLDTKM QRQFFIGVLD IAGFEIFEFN SFEQLCINFT
NEKLQQFFNH HMFVLEQEEY KREGIEWVFI DFGLDLQACI DLLEKPMGIF SILEEQCVFP
KATDATFKAA LYDNHLGKSN NFLKPKGGKG KGAEAHFELV HYAGTVGYNI TGWLEKNKDP
LNETVVGLFQ KSTMSILAIL FKEEEAPAGS KKQKRGSSFM TVSNFYREQL NKLMTTLHST
APHFVRCIVP NEFKQSGVVD AHLIMHQLAC NGVLEGIRIC RKGFPNRLQY PEFKQRYQVL
NPNVIPQGFV DNKKASELLL GSIDLDVNEY KIGHTKVFFR AGILAKLEDM RDERLSKIMT
MLQCRLRGFL MRVEFKKMLE RRIGLKVIQR NTRKFLELRF WGWWKLYNKV KPLLNVARQE
EEMKAKEEEL RNAMSKTQEL LTKVKDMEEK VATLSQEKND LKIQLQAEQD NLMDAEERLT
QMMKTKMELE SQIGDMRERL EEEEGTAASL SATKRKLEGE LSDLKRDLEG LETTLAKTEK
EKQALDHKVR TLTGDLSLRE DSIAKLQKEK RALEELHQKT LDDLQAEEDK VNHLTKSNSK
LNTQIHELED NWEQEKKIRA EVEKARRKAE SDLKMTIDNL NEMERSKLDL EEVVKKRDME
INSVNSKYED EQSLNSTLQR KLKEHQARIE ELEEELEAER AMRAKVEKQR SDLSRDLEDL
SDRLEEAGGA TSAQIEQNRK REAELLKLRR ELEEAALQSE ATASTLRKKH TDSMAELTEH
VENLQRVKSK LEKDKQVMKA EIDDLNASME TVQKSKMNAE AHVRKLEDSL AEANAKVAEL
ERNQAEINAI RTRLQAENSE LSREYEESQS RLNQILRVKT SLTSQVDDYK RQLDEESKSR
STAVVSLANT KHDLDLLKEQ LEEEQGGKTE LQRLVSKLNT EVTTWRTKYE TDAIQRTEEL
EETKRKLAAR LQEAEETAEA AQARAASLEK NKQRLQAEVE DLTIDLEKAN AAAAALDKKQ
RVFDKMLAEW QQKCEELQVE VDSSQKECRM YMTESFKIKT AYEESLEHLE SVKKENKTLQ
EEIKELIDQL GEGGRSVHEL QKLKKKLEIE KDELQVALEE AESSLEVSHR LNVLVQYVKA
FSAWTCRKNH QRAIESLQTS LDAEAKGRAE ALRLKKKMET DLNEMEIQLD HANKNNSELV
KTLKRLQQQL KDLQVQMDED ARQHEELREQ YNLQERRLSL LQTELEEVRS ALEGSERSRK
LLEQEVVEIT ERHNEVNVQN QSLLVVKRKL ESDVQRISNE HEELISEFRS ADERAKKAMT
DAARMAEELR QEQDHCMHLE KIKKNYEITI KDLQAKMEEA EQLALKGGKR TIMKLETRIK
ELETELDGEQ KRHVETVKTL RKNERRLKEL VFQTEEDHKT NQRMQELVEK LQNKMKVYKR
QIEEAEEQAN QTFARYRKTV HELDDAEERA GMAETALNKL RTRHRVAGKG ITSVEIIQVS
KTGSSKTLSE E
//
