ID   S7NP02_MYOBR            Unreviewed;      1255 AA.
AC   S7NP02;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Abnormal spindle-like microcephaly-associated protein like protein {ECO:0000313|EMBL:EPQ19444.1};
GN   ORFNames=D623_10008235 {ECO:0000313|EMBL:EPQ19444.1};
OS   Myotis brandtii (Brandt's bat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC   Myotis.
OX   NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ19444.1, ECO:0000313|Proteomes:UP000052978};
RN   [1] {ECO:0000313|Proteomes:UP000052978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23962925; DOI=10.1038/ncomms3212;
RA   Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA   Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA   Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA   Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA   Krogh A., Wang J., Gladyshev V.N.;
RT   "Genome analysis reveals insights into physiology and longevity of the
RT   Brandt's bat Myotis brandtii.";
RL   Nat. Commun. 4:2212-2212(2013).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; KE164687; EPQ19444.1; -; Genomic_DNA.
DR   AlphaFoldDB; S7NP02; -.
DR   eggNOG; KOG0165; Eukaryota.
DR   Proteomes; UP000052978; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   CDD; cd21223; CH_ASPM_rpt1; 1.
DR   CDD; cd21224; CH_ASPM_rpt2; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   PANTHER; PTHR22706:SF1; ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN ISOFORM X1; 1.
DR   PANTHER; PTHR22706; UNCHARACTERIZED; 1.
DR   Pfam; PF00307; CH; 1.
DR   SMART; SM00033; CH; 2.
DR   SMART; SM00015; IQ; 3.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   PROSITE; PS50021; CH; 2.
DR   PROSITE; PS50096; IQ; 2.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT   DOMAIN          806..942
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          996..1148
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   REGION          292..315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          342..405
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          454..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          974..995
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        292..309
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        387..405
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        490..513
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        978..994
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1255 AA;  141045 MW;  C3D38A4D88B1BB83 CRC64;
     MTFPGELSGY VGRPVFLKHQ CLCRKVPMSR SLWDTIKKKK VSSSSSHKKR ISNIQNVNQT
     FSVPPKADRV RSPLQACENL GGNEGCSPTE NNSLILQENK IPISPISPTF KECHGDTCLP
     LCVRRSTTYT SLHSPKNGEL WTLEGAHMRK EFNGKVITET SFDSLTGING QIEEDGKRSL
     TPNCSSTWNI TQSQGDFLSP DSFVKNSHRA SHKLESVTVS PDTFLKDDSR PRHLESNTIH
     EIYRTILSPD SFLKDNYGLN QKLESESVNP FVSPNQFVRD NMPYLSLSQP TCELSPLSKE
     HSQAPPSPPG QRKNEVLRFI PGNQGANSPK AIFAEPEASE MIPDGHSFTK QKQPAFPAAQ
     DTAGQAHGAQ PRRRPILSAT VTKPKPAGPR ERSREEPSEP KARRCLRSAV GDCGNAAEDQ
     EEEDALHPYL PVIDPAGGNP KGCRRAAPSC KAAFPARKRK SGGGGEDAAG ASAGTGHAGE
     RESKRIHFSP VESRTSTVKK TNMPGTPASQ CRSSRGRPHP KKKADSLAFK TPNSKTHKRT
     PRMVPVAQAS LTFIKRLKTG KYIPRHPMPF AAKNMFYDER WKEKQQQGLT WWLNFILTPD
     DFAVKTHVSE VNAASLLLGG ESHHKLSVPR APTKEEVSLR AYTARRRLNH LRHAACRLFT
     SESMVKAIKK LEVEIAARRL AVRRDRHLWK DVGERQKVLS WLLSYNPLWL RIGLETVFGE
     LIALEDNSDV TGLAVFILHR LLWNPDIAAE YRHPSVPHLY RDGHEEALSA FTLKKLLLLV
     CFLDRAKLSR LIDHDPCLFC KDAEFKASRD VLLAFSRGFL SGEGDLSRHL SWLGLPVSHV
     QTPLDEFDFA VTNLAVDLQC GVRLVRTMEL LTRNWDLSKQ LRIPAISRLQ KMHNVDLALQ
     ALQSRGISLQ DEQGGAILAK DIVDRHREKT LALLWKIALA FQVDISLNLD ELKEEIDFLK
     RTWRVKRSTP ARSRPADAVL SEKTDTRPSD SSEQRPESIR LLMEWVQAVC AFYSVKVENF
     TVSFSDGRVL CYLIHHYHPR CVPLDAIRQR TSQTVECAQS GSVVLNSSSE SDESCLDLSL
     KALELAGKAP ELHRELLENE RRNFQLVSSA ARDLGGIPAM VQHADMSNTI PDEKVVVTYL
     SFLCARLLDL RRETRAARRI QAAWREYKLR ADLRRHQERD QAARIIQAAV LGFLTRRRLR
     KEAQAALAVQ RRWRRLCRRR AVLRAQQEQL EKAQSQAASV IQVEHPGALE FGKFQ
//