ID   S7PDM6_MYOBR            Unreviewed;       524 AA.
AC   S7PDM6;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Heat shock 70 kDa protein 13 {ECO:0000256|ARBA:ARBA00018765};
DE   AltName: Full=Stress-70 protein chaperone microsome-associated 60 kDa protein {ECO:0000256|ARBA:ARBA00031426};
GN   ORFNames=D623_10032778 {ECO:0000313|EMBL:EPQ06017.1};
OS   Myotis brandtii (Brandt's bat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC   Myotis.
OX   NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ06017.1, ECO:0000313|Proteomes:UP000052978};
RN   [1] {ECO:0000313|Proteomes:UP000052978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23962925; DOI=10.1038/ncomms3212;
RA   Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA   Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA   Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA   Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA   Krogh A., Wang J., Gladyshev V.N.;
RT   "Genome analysis reveals insights into physiology and longevity of the
RT   Brandt's bat Myotis brandtii.";
RL   Nat. Commun. 4:2212-2212(2013).
CC   -!- FUNCTION: Has peptide-independent ATPase activity.
CC       {ECO:0000256|ARBA:ARBA00002077}.
CC   -!- SUBUNIT: Binds UBQLN2. {ECO:0000256|ARBA:ARBA00011671}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC       {ECO:0000256|ARBA:ARBA00004240}. Microsome
CC       {ECO:0000256|ARBA:ARBA00004144}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
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DR   EMBL; KE161952; EPQ06017.1; -; Genomic_DNA.
DR   RefSeq; XP_005863508.1; XM_005863446.2.
DR   AlphaFoldDB; S7PDM6; -.
DR   GeneID; 102255865; -.
DR   KEGG; myb:102255865; -.
DR   CTD; 6782; -.
DR   eggNOG; KOG0101; Eukaryota.
DR   OrthoDB; 143at2759; -.
DR   Proteomes; UP000052978; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   CDD; cd10237; HSPA13-like_NBD; 1.
DR   Gene3D; 3.30.30.30; -; 1.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   InterPro; IPR042048; HSPA13.
DR   PANTHER; PTHR19375:SF169; HEAT SHOCK 70 KDA PROTEIN 13; 1.
DR   PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR   Pfam; PF00012; HSP70; 2.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022848};
KW   Microsome {ECO:0000256|ARBA:ARBA00022848};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU003322};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW   Stress response {ECO:0000313|EMBL:EPQ06017.1}.
FT   REGION          365..393
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..391
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   524 AA;  57664 MW;  674D3F4547C56C6A CRC64;
     MVKKVLSLVR HVASLAASEQ ENYISQRSAG RPAAWGRRLP SGTVIPNLFG RTVMAGEMTI
     LGSAVLTLLL AGYLSQQYLP LPTPKVIGID LGTTYCSVGV FFPGTGKVKV IPDENGHISI
     PSMVSFTDHD VYVGYESLEL ADSNPQNTIY DAKRFIGKIF TPEELEAEIG RYPFKVLNKN
     GMVEFSVTSN ETITVSPEYV GSRLLLKLKE MAEEYLGMPV ANAVISVPAE FDLKQRNSTI
     EAANLAGLKI LRVINEPTAA AMAYGLHKAD VFHVLVIDLG GGTLDVSLLN KQGGMFLTRA
     MSGNNKLGGQ DFNQRLLQYL YKQIYQTYGF LPSRKEEIHR LRQAVEMVKL NLTLHQSAQM
     SVLLTVEEKD KKETPSSDTE LSKDRLSPAD DHHVSSMFGA GLSEKKSGES QVLFETEISR
     ELFDTLNEDL FQKILVPIQQ VLKEGHLEKT EVDEVVLVGG STRIPRIRQV IQEFFGKDPN
     TSVDPDLAVV TGVAIQAGID GGSWPLQVSA LEIPNKHLQK TNFN
//