ID S7PE96_MYOBR Unreviewed; 242 AA.
AC S7PE96;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Coiled-coil domain-containing protein 103 {ECO:0000313|EMBL:EPQ06262.1};
GN ORFNames=D623_10009503 {ECO:0000313|EMBL:EPQ06262.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ06262.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- FUNCTION: Dynein-attachment factor required for cilia motility.
CC {ECO:0000256|ARBA:ARBA00004048}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000256|ARBA:ARBA00004230}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the CCDC103/PR46b family.
CC {ECO:0000256|ARBA:ARBA00008470}.
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DR EMBL; KE161975; EPQ06262.1; -; Genomic_DNA.
DR RefSeq; XP_005863920.1; XM_005863858.2.
DR RefSeq; XP_005863921.1; XM_005863859.2.
DR RefSeq; XP_005863922.1; XM_005863860.2.
DR AlphaFoldDB; S7PE96; -.
DR GeneID; 102256769; -.
DR KEGG; myb:102256769; -.
DR CTD; 388389; -.
DR eggNOG; ENOG502RY3P; Eukaryota.
DR OrthoDB; 3027031at2759; -.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0036157; C:outer dynein arm; IEA:InterPro.
DR GO; GO:0070286; P:axonemal dynein complex assembly; IEA:InterPro.
DR InterPro; IPR042422; CC103.
DR InterPro; IPR031733; Dynein_attach_N.
DR InterPro; IPR025986; RPAP3-like_C.
DR PANTHER; PTHR28572; COILED-COIL DOMAIN-CONTAINING PROTEIN 103; 1.
DR PANTHER; PTHR28572:SF1; COILED-COIL DOMAIN-CONTAINING PROTEIN 103; 1.
DR Pfam; PF15867; Dynein_attach_N; 1.
DR Pfam; PF13877; RPAP3_C; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT DOMAIN 7..74
FT /note="Dynein attachment factor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15867"
FT DOMAIN 98..188
FT /note="RNA-polymerase II-associated protein 3-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF13877"
FT REGION 203..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 242 AA; 27537 MW; 2810C1EB580C4F3C CRC64;
MERNDIIDFK ALEKELQAAI TADEKYQREN AAKFRAVEQR VASYEEFRGI VLASHLKPLE
RKDKIGGTRT VPWNCHTTPR RTSPDETTEI SQEKTLLQPE TSAEFYRDWR RYLRSGPERY
QALLQLGGPK LGHLFQTDVG FGLLGELLMA LAEHVRPADR LVVLGILRGL ASTGRFALNL
SLMSHAERES CRSLFQKLQA MGTPRPMKEG LSQEEQGLEE QPGGLQEEES LLQELLELYQ
VD
//
