ID S7VK92_DESML Unreviewed; 573 AA.
AC S7VK92;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=TrkA-N domain protein {ECO:0000313|EMBL:EPR44988.1};
GN ORFNames=dsmv_1024 {ECO:0000313|EMBL:EPR44988.1};
OS Desulfococcus multivorans DSM 2059.
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfococcaceae; Desulfococcus.
OX NCBI_TaxID=1121405 {ECO:0000313|EMBL:EPR44988.1, ECO:0000313|Proteomes:UP000014977};
RN [1] {ECO:0000313|EMBL:EPR44988.1, ECO:0000313|Proteomes:UP000014977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2059 {ECO:0000313|EMBL:EPR44988.1,
RC ECO:0000313|Proteomes:UP000014977};
RX PubMed=23950126;
RA Brown S.D., Hurt R.A.Jr., Gilmour C.C., Elias D.A.;
RT "Draft genome sequences for three mercury-methylating, sulfate-reducing
RT bacteria.";
RL Genome Announc. 1:e00618-e00613(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPR44988.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ATHJ01000011; EPR44988.1; -; Genomic_DNA.
DR RefSeq; WP_020875215.1; NZ_FUWN01000008.1.
DR AlphaFoldDB; S7VK92; -.
DR STRING; 897.B2D07_12020; -.
DR PATRIC; fig|1121405.3.peg.186; -.
DR eggNOG; COG0569; Bacteria.
DR eggNOG; COG1226; Bacteria.
DR OrthoDB; 9799090at2; -.
DR Proteomes; UP000014977; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833:SF9; POTASSIUM CHANNEL PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR Pfam; PF02254; TrkA_N; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS51202; RCK_C; 2.
DR PROSITE; PS51201; RCK_N; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014977};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 132..253
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 260..347
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 357..474
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 484..565
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 573 AA; 63501 MW; 90B252269C6D8C59 CRC64;
MKTMTTQLAL LMQLSRRKSN MRLLIRFSMV LILFFALYTV LFHVLMLYEG RRYSWITGLY
WTLTTMSTLG FGDITFSSDI GKFFSVVVLL SGIIFLLIIL PFTFIQFFYA PWLDEQNKAR
APRAVAESLS GHLIFTYFDA VAVNLIQKLG QYGINYVILT AELQKALDLH DQGYAVVVGD
LDDPQTYHRL NIDRAAMVIV LNDDVASTNI IFTIREANAN VVTVTNADAD DSLDILEMAG
STHVLQFTKM LGQALARRVH GVSMKANVVG RFDQLLIAEA PVMRTWLQGK SLAESRLREV
TGVTVVGIWE EGQFRIPGPQ SLIGESTVLV LAGTEAQLDR FDRSIGGGRE KQLNSGPVVV
LGGGRVGMAV ANTLKARDID YRVVEKKTGI AAQDPHFIQG SAADLETLVK ASIHETPSVI
ITTHDDNLNI YLTIYCRRLR PDVQIISRAS LDRNINTLHR AGANLVMSYS SLVTATILNL
LHPQKILMLS EGLNVFRTAL NPKLENKALL DIQVRENTQC SVVAVKRGED LIINPDPTII
LEPGDELLLI GLAESEKKFI EKYPAPASTS PEP
//
