ID S7XVQ6_SPRLO Unreviewed; 443 AA.
AC S7XVQ6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Eukaryotic translation initiation factor eIF2A {ECO:0000313|EMBL:EPR79978.1};
GN ORFNames=SLOPH_349 {ECO:0000313|EMBL:EPR79978.1};
OS Spraguea lophii (strain 42_110) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Spraguidae;
OC Spraguea.
OX NCBI_TaxID=1358809 {ECO:0000313|EMBL:EPR79978.1, ECO:0000313|Proteomes:UP000014978};
RN [1] {ECO:0000313|Proteomes:UP000014978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=42_110 {ECO:0000313|Proteomes:UP000014978};
RX PubMed=23990793; DOI=10.1371/journal.pgen.1003676;
RA Campbell S.E., Williams T.A., Yousuf A., Soanes D.M., Paszkiewicz K.H.,
RA Williams B.A.P.;
RT "The genome of Spraguea lophii and the basis of host-microsporidian
RT interactions.";
RL PLoS Genet. 9:E1003676-E1003676(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPR79978.1}.
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DR EMBL; ATCN01000054; EPR79978.1; -; Genomic_DNA.
DR AlphaFoldDB; S7XVQ6; -.
DR STRING; 1358809.S7XVQ6; -.
DR VEuPathDB; MicrosporidiaDB:SLOPH_349; -.
DR HOGENOM; CLU_035147_0_0_1; -.
DR InParanoid; S7XVQ6; -.
DR OMA; GYAVCHS; -.
DR OrthoDB; 1343922at2759; -.
DR Proteomes; UP000014978; Unassembled WGS sequence.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR011387; TIF2A.
DR InterPro; IPR013979; TIF_beta_prop-like.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13227; EUKARYOTIC TRANSLATION INITIATION FACTOR 2A; 1.
DR PANTHER; PTHR13227:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 2A; 1.
DR Pfam; PF08662; eIF2A; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 4: Predicted;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:EPR79978.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000014978}.
FT DOMAIN 163..343
FT /note="Translation initiation factor beta propellor-like"
FT /evidence="ECO:0000259|Pfam:PF08662"
SQ SEQUENCE 443 AA; 52555 MW; 259CDBABB26ECCA1 CRC64;
MIEDTVVVLC ESGIILGLFN DEKIIESDGY ERYNNKLLIK NKNSIYFYDI VSGVKGETFQ
FNDIKIMKIN GEDSAGILTY DKKLYLIRNN KIIKELQDVE QFIYSGKYLS TQYKGELTFY
HENNNILTLK NVNEFYQFND ILITLQKKKT ISIYKDKKMV FTKEFKNIEG LECKINNKEN
KIMLLLTTEY VDNNYFGTKE LYLYFLDENK FRFLDYKIVN DYQFLDDKYV ICYGHQPSKI
VICQNRIKEE YPSGFRNRVY YNSNMKMVCF CGMDNLSGNI EIFDCTKRDT IFKTKMLGVS
EIMWSPSGTY LCTAVTNILK VDNKIVIYDY YGRKIAEREF KNLERVDWVG NSTFKKLEEP
KVKNLEQEEV YIPPNRRGRI EKKVKTHKPI KKQVKVENTE ELKEKIQIIE ILKKKIQNNE
KLSLEEMNLV LKESDIKKKL DKK
//
