ID S9Q2Z1_SCHOY Unreviewed; 331 AA.
AC S9Q2Z1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Exosome subunit Rrp4 {ECO:0000313|EMBL:EPX74477.1};
GN ORFNames=SOCG_01961 {ECO:0000313|EMBL:EPX74477.1};
OS Schizosaccharomyces octosporus (strain yFS286) (Fission yeast)
OS (Octosporomyces octosporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=483514 {ECO:0000313|EMBL:EPX74477.1};
RN [1] {ECO:0000313|EMBL:EPX74477.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YFS286 {ECO:0000313|EMBL:EPX74477.1};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
RN [2] {ECO:0000313|EMBL:EPX74477.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=YFS286 {ECO:0000313|EMBL:EPX74477.1};
RG The Broad Institute Genome Sequencing Platform;
RA Nusbaum C., Russ C., Rhind N., Niki H., Allshire R., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Birren B.;
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RRP4 family.
CC {ECO:0000256|ARBA:ARBA00009155}.
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DR EMBL; KE503206; EPX74477.1; -; Genomic_DNA.
DR RefSeq; XP_013015909.1; XM_013160455.1.
DR AlphaFoldDB; S9Q2Z1; -.
DR EnsemblFungi; EPX74477; EPX74477; SOCG_01961.
DR GeneID; 25030939; -.
DR VEuPathDB; FungiDB:SOCG_01961; -.
DR eggNOG; KOG3013; Eukaryota.
DR HOGENOM; CLU_034114_3_0_1; -.
DR OMA; GVNGFIW; -.
DR OrthoDB; 5472588at2759; -.
DR Proteomes; UP000016088; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:EnsemblFungi.
DR GO; GO:0000177; C:cytoplasmic exosome (RNase complex); IEA:EnsemblFungi.
DR GO; GO:0000176; C:nuclear exosome (RNase complex); IEA:EnsemblFungi.
DR GO; GO:0005730; C:nucleolus; IEA:EnsemblFungi.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0071028; P:nuclear mRNA surveillance; IEA:EnsemblFungi.
DR GO; GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IEA:EnsemblFungi.
DR GO; GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IEA:EnsemblFungi.
DR GO; GO:0034427; P:nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'; IEA:EnsemblFungi.
DR GO; GO:0071051; P:polyadenylation-dependent snoRNA 3'-end processing; IEA:EnsemblFungi.
DR GO; GO:0034475; P:U4 snRNA 3'-end processing; IEA:EnsemblFungi.
DR CDD; cd22525; KH-I_Rrp4_eukar; 1.
DR CDD; cd05789; S1_Rrp4; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR025721; Exosome_cplx_N_dom.
DR InterPro; IPR026699; Exosome_RNA_bind1/RRP40/RRP4.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR048565; RRP4_S1.
DR InterPro; IPR003029; S1_domain.
DR PANTHER; PTHR21321:SF4; EXOSOME COMPLEX COMPONENT RRP4; 1.
DR PANTHER; PTHR21321; PNAS-3 RELATED; 1.
DR Pfam; PF14382; ECR1_N; 1.
DR Pfam; PF15985; KH_6; 1.
DR Pfam; PF21266; RRP4_S1; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF110324; Ribosomal L27 protein-like; 1.
PE 3: Inferred from homology;
KW Exosome {ECO:0000256|ARBA:ARBA00022835};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 112..192
FT /note="S1 motif"
FT /evidence="ECO:0000259|SMART:SM00316"
SQ SEQUENCE 331 AA; 37428 MW; 7292730FD13B3081 CRC64;
MVTILKPEET YAFTKEYERD EIDAKMVMSD EENEMEVDEE DEYPAEMELE DEAAGVKNMV
APGQLITDDP QFMRGHGTYF EDGGIYASVT GVVQRVNKLI SVRPFKTKYV PEIGDLIIGR
ITEVQPKRWK VDIGSKQDAV LMLSSINLPG GVQRRKLETD ELQMRNYFQE GDRLVAEVQQ
YFSDGSVSIH TRSLKYGKLR NGVFLKVPSS LVVRSKSHIF NLPGGVDLIL SVNGYAWISK
HNKNQESSVS ITRLEEEASE AIYSNENDEV DVYTRLNISR IYICVRALAN RGLPLTEAAI
LNFYEASLLY GDLQQLTSPK ILDQIAVEAM H
//
