ID S9R034_SCHOY Unreviewed; 749 AA.
AC S9R034;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=PX/PXA domain-containing protein {ECO:0000313|EMBL:EPX71850.1};
GN ORFNames=SOCG_03786 {ECO:0000313|EMBL:EPX71850.1};
OS Schizosaccharomyces octosporus (strain yFS286) (Fission yeast)
OS (Octosporomyces octosporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=483514 {ECO:0000313|EMBL:EPX71850.1};
RN [1] {ECO:0000313|EMBL:EPX71850.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YFS286 {ECO:0000313|EMBL:EPX71850.1};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
RN [2] {ECO:0000313|EMBL:EPX71850.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=YFS286 {ECO:0000313|EMBL:EPX71850.1};
RG The Broad Institute Genome Sequencing Platform;
RA Nusbaum C., Russ C., Rhind N., Niki H., Allshire R., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Birren B.;
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KE503207; EPX71850.1; -; Genomic_DNA.
DR RefSeq; XP_013019150.1; XM_013163696.1.
DR AlphaFoldDB; S9R034; -.
DR EnsemblFungi; EPX71850; EPX71850; SOCG_03786.
DR GeneID; 25032754; -.
DR VEuPathDB; FungiDB:SOCG_03786; -.
DR eggNOG; ENOG502RM76; Eukaryota.
DR HOGENOM; CLU_371373_0_0_1; -.
DR OMA; FVNRCII; -.
DR OrthoDB; 2727031at2759; -.
DR Proteomes; UP000016088; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06093; PX_domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR22775:SF47; MEIOTICALLY UP-REGULATED GENE 122 PROTEIN; 1.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR SMART; SM00313; PXA; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS51207; PXA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 93..266
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT REGION 462..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..524
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 749 AA; 85147 MW; CEF395CCEF38FDF5 CRC64;
MLMQWDLPTA QKAVFNLGNH PRYIGIFFCF ILLFYFFHAF FGGLVYFALG IIVGVCALGL
THENGNIVLN IKHPKVEGPS QCIPQRYPQH NLPKELEAPL LLLITKLTHH YIHGWYSHVS
SDMSFVKEVE NTIGYIMRNF YSYLSTQDSS YLIFEMLKNV LNTLTLLLSD LNVFLSKKMP
IAEFAVRYPN SAVAKMLDKA ANEQALRSQA SAMITKFCKS EDAACLPLHV LLREVLAMQV
FKKITTHCAK PVFVNRCIIL CLSPSKEKDE CISRNRYINR CLLNKTLKDS SPLSTLPTDD
SPQTSYSFNN ALFEAEIHIQ YRSLDAKELI SPIKDKKNLK FIITVHSSYL DIPPWIVYRT
YSSLKSMYKD LRKEFLHATG APLMFPRWRN QTYGHFRQNL SAYLNGIVQV PKLSNDAVVR
HFFCKSLSFQ PLPDDIVDGM ERQNNSSFST VSNKILEVTR IVSGRSGHSK TSEDSSTSEP
TWNTKFERSM LEDTDLSNIP SNELSSMEDD NQSFENKNEG KNHSRCSSES NPFGDEPSAF
RIQEEALKEI IDSGFALFGE LSCLNPKTWF FRRTVLSVLK SLLLYGPVDV SGIVEKMLKD
HVFAKLSNTQ LLGDFFTSLI LNIWPEEKEK VQEHLRNLQQ AKAHENEDGA NWDSAPGNKD
DTDLYLEEAM KNSLFNSHSA FAVQQKNEEQ MRVEAKELFL NNAYADNASF LGPLTSGDSL
RVLFDLLQES DLVEGFLAHV LSNALHSII
//
