ID S9S5J5_9RALS Unreviewed; 803 AA.
AC S9S5J5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:EPX99427.1};
GN ORFNames=C404_02445 {ECO:0000313|EMBL:EPX99427.1};
OS Ralstonia sp. AU12-08.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=1235457 {ECO:0000313|EMBL:EPX99427.1, ECO:0000313|Proteomes:UP000015343};
RN [1] {ECO:0000313|EMBL:EPX99427.1, ECO:0000313|Proteomes:UP000015343}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AU12-08 {ECO:0000313|EMBL:EPX99427.1,
RC ECO:0000313|Proteomes:UP000015343};
RX PubMed=24503988;
RA Zhang L., Morrison M., Rickard C.M.;
RT "Draft Genome Sequence of Ralstonia pickettii AU12-08, Isolated from an
RT Intravascular Catheter in Australia.";
RL Genome Announc. 2:e00027-14(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPX99427.1}.
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DR EMBL; ASZV01000005; EPX99427.1; -; Genomic_DNA.
DR AlphaFoldDB; S9S5J5; -.
DR PATRIC; fig|1235457.3.peg.494; -.
DR eggNOG; COG2199; Bacteria.
DR Proteomes; UP000015343; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000313|EMBL:EPX99427.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:EPX99427.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 520..583
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 672..803
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 803 AA; 85248 MW; BBB7BB2577DDB2E2 CRC64;
MFRLLPGVVF AALVPFAGLI AVAVSTVYDD TRQEIDSRLD QAISQAARPI DARLASIIDR
LSAATEGASN LHKPADGQTW LDTHADLRGA FDNVLVVGAD GTLLADAPAL PERRGDNMAD
HPIFQTVRDT RRLYIPEPFL APAGKRPVAS FAAPLHSNDG SFAGLVIGSI ELSRNPMLAD
LEAVRMGRTG RLVVVSEGGK YIVAPDRSRL LQQAPDLAAL PTSARALAQG WSQGAEFTPP
GQAPVIVGYR RLNAVPWSVG VWWPVQEAYA GAARTARTLI AAGIAFGAVC LLFAWFWIER
AVSPLERLRH EVEGGLPIHP VAPTSGRPPL HDAHPPGPLT RLGELADPQV STFDPTTEVG
ALAVRVGHLA KYWEQALEIS EQDVAFFRAL AEQAPVGLAF LDRALAVPFA NVRFERLLGA
SAQAISLALQ AKEGDPVPPA ARAVATALAH LPRAPLALAD QPVVIATGQG AAIGAVLLTA
RPIGGAGAPL AGWIVAVVDS TREQRAKEAL EQEVRAALLV LDAIQEPLLT IDGDGIVTHA
SRAIETLVGT HPARAVGQSI NRLLHLMEHD SGRRVIPTQL LRSGGTLSGN LRLERADGRR
HDVELSWGPL PGTSGSGVLV LRDVSATRET VQRIAWDATH DVLTGLLNRR GFDATLRAQV
EAHRGGNPVT RAPLALIMID LDGFKTINDR YGHAAGDDVL RGVAELVVQN TRTQDYVARL
GGDEFAVILP NCDMQAAVTF ADRIRATLAR QPLLAAGARA EIALSQGVVE LHADDADVSA
FLARADAACY RAKNEGRGAI ASD
//
