ID S9TPR6_9TRYP Unreviewed; 1098 AA.
AC S9TPR6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Calcium/potassium channel (CAKC) {ECO:0000313|EMBL:EPY20312.1};
GN ORFNames=STCU_09055 {ECO:0000313|EMBL:EPY20312.1};
OS Strigomonas culicis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Strigomonadinae; Strigomonas.
OX NCBI_TaxID=28005 {ECO:0000313|EMBL:EPY20312.1, ECO:0000313|Proteomes:UP000015354};
RN [1] {ECO:0000313|EMBL:EPY20312.1, ECO:0000313|Proteomes:UP000015354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23560078;
RA Motta M.C., Martins A.C., de Souza S.S., Catta-Preta C.M., Silva R.,
RA Klein C.C., de Almeida L.G., de Lima Cunha O., Ciapina L.P., Brocchi M.,
RA Colabardini A.C., de Araujo Lima B., Machado C.R., de Almeida Soares C.M.,
RA Probst C.M., de Menezes C.B., Thompson C.E., Bartholomeu D.C., Gradia D.F.,
RA Pavoni D.P., Grisard E.C., Fantinatti-Garboggini F., Marchini F.K.,
RA Rodrigues-Luiz G.F., Wagner G., Goldman G.H., Fietto J.L., Elias M.C.,
RA Goldman M.H., Sagot M.F., Pereira M., Stoco P.H., de Mendonca-Neto R.P.,
RA Teixeira S.M., Maciel T.E., de Oliveira Mendes T.A., Urmenyi T.P.,
RA de Souza W., Schenkman S., de Vasconcelos A.T.;
RT "Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their
RT Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae
RT Family.";
RL PLoS ONE 8:E60209-E60209(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPY20312.1}.
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DR EMBL; ATMH01009055; EPY20312.1; -; Genomic_DNA.
DR EnsemblProtists; EPY20312; EPY20312; STCU_09055.
DR OrthoDB; 49040at2759; -.
DR Proteomes; UP000015354; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR048735; Slowpoke-like_C.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF10; SLOWPOKE 2, ISOFORM D; 1.
DR Pfam; PF03493; BK_channel_a; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR Pfam; PF21014; Slowpoke_C; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000313|EMBL:EPY20312.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000015354};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 112..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 256..330
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 475..568
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT DOMAIN 1030..1088
FT /note="Ca2+-activated K+ channel Slowpoke-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21014"
FT REGION 655..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..683
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1098 AA; 126157 MW; DB29438D9CC1A0DA CRC64;
MLFFFWXCER FSIIERIECI DLCKAMSKRA DMCEPVDLTL TRGTPHQKLP PIRRYWRTRT
VRRNKERLTE SENYNQALIS SHNVPDHHTE NTTEFRYISG PKYFFQRFVR QYPVAALCVW
VFLFLVELSS VVLYVIQSTL SDDVSWVNYD KSEHSGWFYA RSVLAIVSML QLFFAYSLSL
LTIFVVVSTS LYQIVIFFMA FSPNMGWVSR LYVPYFLRCW SLRQYFLFIL DSVALMSTRE
RKLDLMRLSA GPLTLFICMV FTAAGIFRID QTFRGYPLNI AVAIYFTVVT VSTVGFGDVT
PRTKEGMAIT IVIIFVFISK MPTFIQVIRS TAKILKAFRS YKGRKNHFIV YGLLTREEVI
SILDEVFCLY PMKAVCFCNK EFAPDVLAIG RHPTYRLRCT FLMVDNLDVF ALRRMKASEA
AGVIVFPIRE GYSSRVDDDV MLTSLIFERL MPSLPQYIWL RYGLHAKLLK GQRASVIDEH
MKKNIMATAL LLPGIVPFLV NIVRTAWASG VEPDNLWTKD GMHDWKSQYE FSRRNVISSC
VVPSRFVDLP LRDVVSKFKY YEVLVVGVEE QARKIMRLDL DYVLEDGDVL MVIYERNRNG
LAPALQNFTQ LGPLEEIDSQ MYGNHFCHNF SENELLHGNM NASFVFYPYK AGSPSPTADG
NNPVEPAHAR PEDADKEAEA VSEEEVKRRL LALPFVPTGP QGVDLQSLSM GSRNAERLDT
LITRHDEAVK DPYTTEEERF ELVGNIQEQI VSLVMKITEN EGNSASDKAL SEEGAEDQEE
VFLFVDQTTS ILRKTNMSIY EDVISQTIAQ YELYIMFQCI RSIHAKSKLS LLTLRKHSPD
FLRTWQDIFG KPMRYIRGQG SLDAHLNYAL TADADISKVR GILLYCSQMG PRDFGDVPIF
SVENNVRELL EWNARSREEY GNLPEQNIMV ELQSLTSSVK VAPFHNDPEW RRRGEQNFQE
TLAFMMGRCF SSNMLLPLMV HCHRDSRIDS FFEMVLNLSS TSEMFDMAMW TSRISHSQTL
FKLCGNKSLQ FETYGDAFEF LLKQRSCVAI GVYRLFPPSE MLSGSSRYFV TNPALSMPLT
SDDIVYCLDG GAPVEAEE
//
