ID S9TS00_9TRYP Unreviewed; 1740 AA.
AC S9TS00;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
DE Flags: Fragment;
GN ORFNames=STCU_08682 {ECO:0000313|EMBL:EPY21132.1};
OS Strigomonas culicis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Strigomonadinae; Strigomonas.
OX NCBI_TaxID=28005 {ECO:0000313|EMBL:EPY21132.1, ECO:0000313|Proteomes:UP000015354};
RN [1] {ECO:0000313|EMBL:EPY21132.1, ECO:0000313|Proteomes:UP000015354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23560078;
RA Motta M.C., Martins A.C., de Souza S.S., Catta-Preta C.M., Silva R.,
RA Klein C.C., de Almeida L.G., de Lima Cunha O., Ciapina L.P., Brocchi M.,
RA Colabardini A.C., de Araujo Lima B., Machado C.R., de Almeida Soares C.M.,
RA Probst C.M., de Menezes C.B., Thompson C.E., Bartholomeu D.C., Gradia D.F.,
RA Pavoni D.P., Grisard E.C., Fantinatti-Garboggini F., Marchini F.K.,
RA Rodrigues-Luiz G.F., Wagner G., Goldman G.H., Fietto J.L., Elias M.C.,
RA Goldman M.H., Sagot M.F., Pereira M., Stoco P.H., de Mendonca-Neto R.P.,
RA Teixeira S.M., Maciel T.E., de Oliveira Mendes T.A., Urmenyi T.P.,
RA de Souza W., Schenkman S., de Vasconcelos A.T.;
RT "Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their
RT Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae
RT Family.";
RL PLoS ONE 8:E60209-E60209(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPY21132.1}.
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DR EMBL; ATMH01008682; EPY21132.1; -; Genomic_DNA.
DR EnsemblProtists; EPY21132; EPY21132; STCU_08682.
DR OrthoDB; 169277at2759; -.
DR Proteomes; UP000015354; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00038; CAP_ED; 3.
DR Gene3D; 2.60.120.10; Jelly Rolls; 3.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR10217:SF435; POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN EAG; 1.
DR PANTHER; PTHR10217; VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR SMART; SM00100; cNMP; 2.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 3.
DR PROSITE; PS50042; CNMP_BINDING_3; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015354}.
FT DOMAIN 340..429
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 480..588
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 1..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 226..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 875..915
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1642..1675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1696..1718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..659
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1740
FT /evidence="ECO:0000313|EMBL:EPY21132.1"
SQ SEQUENCE 1740 AA; 191228 MW; DF68CB07F5AF3D04 CRC64;
MKRGFRSDSV QHRPTNVSPA GFRSQSLQVS TMRSTPKPTR PAPTAARKAP APEERRPEIP
RGPMTSPRRP GSGLLPSPRD SSIGGTSMNP KLRRTSVLTV AAAMQQQQAP KNKNEPVDFN
APESQEAVRK LQKMFGPILL KRVLKMREKK RWKAYPPREY TMEAVIKAIV ASKCALAEWP
IDLLEQLCAD VVFQYYKPKD VLVYAGEPHV SSGLIVLLYG QVTERRKDKN KSRTQTSSPH
SPDRPIKSQK QRTRYSPDVL CVQSVLCEDR NASSIKASEA VDVAIISSRL IWELINSFVL
ESSKAPMLLE RFRQTVIPNR TEMMLSHYYA TSVLLMRSWM WPFLSGSDRV KLARSMEVKV
LNIGDALFEE GSVCPQIYFL RRGSLTVVVK GEPLAVVEPG AAFGEVSVVF NEARNCSVVA
GSICELYALH GNELYHRFKK YPELIKLITY KSLERRQLWL TDGKLRDVFS LVSILGGVPC
LSHTTESMRE ELARRAQTRT VPMKHTIVRQ NTPCTELFVI GRGSVLVGGK RAVAIVPIAS
ATGDGEVRSV GDYFGELFLW AHLSPLDVVS ETTLDLWVLS KEAVLEVLEL NKAQVQAEEV
CRQGISLYKT QHGDTSIVEG YERPVSSLNT SGMAVRRGST GRTSSAASNG GGRRHSLASN
SKASVEEEDS ERTLTNFDWT GYVKERTVAQ EGTMWRATQR ELRDVDKATE KMLRNKVQAL
ISVPPTLPPN AADCDFPGEV NDLQAIIVEQ LLLIATEEQP RFLKQINDSN LRLITEGGVD
EYEEPEAEVH VEDLGATDEF VPVEGIAKVE EIGSINSSEE VDEEGNQSLP FKNTMGMDNA
SFDRSGSNFI SGPLQLGSYA RLGSPGRKMS LPLDESTGAF PNMGARPSIS RSHLVRPPSG
LPPNSDARSP RNSIQRPISA SEQLVLASQH RVRPASVDYS QQGKVNAEKS VSALDRFVKI
EDKNYFNSVV KMLPLQEGEV WIPDEEEDET GPLMLMLLHV RSCARLNGDV ARGGATFTVK
VLKGSRVLLI TSAQLGSSTD EGTHIRWPVG LASFVKFIHR GVELTFRLTH MTDTNERVVY
EGTFQTALIG DKGGMGRCNV HMHTVKYDQR DTDSDDMEDP SLAPHLTVVV LAAMASSYKG
LQQRLEANTT QVIRDIADDT SRHRAASNVT NYNEAHIQIL AVEGLKHRID ASVRVTCTGA
DETETLLLNT PHVVPKSRNP CWCADGAYLA LRSEGLIKFE LFHKDQAIGS YRAFLDDIVF
GGEGIRRVPL AAAHIEEPLG TLVVHVVSSS ASTKTENRES ERVLLLHVQE LQVKNKDEYI
IPPDLFAVVR HAGSDKTIMR TPLRFGRFNA AYSMEEASCL LVLPSVVGSS ASYTIEVFDS
DERSRIAEGT ATVTDEGLGP DHQYIIPLGD HVQVQVHTQL LSVWDASALQ RPAVRQEDHF
KRDAPLTVVH IERCSFIDLQ DPDNVMRTEA LATLWCAGFE CLRTTPRDYF TESPFAWAME
EASVALRVNP SDLTESAVLS LYDGLIDAAD LVGEVTLPLT DLVRTGEFTY SVYPVDTHGR
RKGHRPRGTV TVRTLCGRAN GAVLAPGGSN ASTALLEDSA GTFYSTALLD APIGAGRRRA
APAQVRLCLT NVYQVLPKAG QQDGRGGAAG GHVHRAEGGA ARRGGPVTPR GTWSEGGAVM
KVRDFPCEIT VRVTAANVQP RADGEGSPTG PDPAPPKRSV VVGEAKVLLT EVEATEARMF
//
