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Database: UniProt
Entry: S9UZ70_9TRYP
LinkDB: S9UZ70_9TRYP
Original site: S9UZ70_9TRYP 
ID   S9UZ70_9TRYP            Unreviewed;       578 AA.
AC   S9UZ70;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   11-NOV-2015, entry version 8.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=AGDE_07079 {ECO:0000313|EMBL:EPY36107.1};
OS   Angomonas deanei.
OC   Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae;
OC   Strigomonadinae; Angomonas.
OX   NCBI_TaxID=59799 {ECO:0000313|EMBL:EPY36107.1, ECO:0000313|Proteomes:UP000015341};
RN   [1] {ECO:0000313|EMBL:EPY36107.1, ECO:0000313|Proteomes:UP000015341}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23560078;
RA   Motta M.C., Martins A.C., de Souza S.S., Catta-Preta C.M., Silva R.,
RA   Klein C.C., de Almeida L.G., de Lima Cunha O., Ciapina L.P.,
RA   Brocchi M., Colabardini A.C., de Araujo Lima B., Machado C.R.,
RA   de Almeida Soares C.M., Probst C.M., de Menezes C.B., Thompson C.E.,
RA   Bartholomeu D.C., Gradia D.F., Pavoni D.P., Grisard E.C.,
RA   Fantinatti-Garboggini F., Marchini F.K., Rodrigues-Luiz G.F.,
RA   Wagner G., Goldman G.H., Fietto J.L., Elias M.C., Goldman M.H.,
RA   Sagot M.F., Pereira M., Stoco P.H., de Mendonca-Neto R.P.,
RA   Teixeira S.M., Maciel T.E., de Oliveira Mendes T.A., Urmenyi T.P.,
RA   de Souza W., Schenkman S., de Vasconcelos A.T.;
RT   "Predicting the Proteins of Angomonas deanei, Strigomonas culicis and
RT   Their Respective Endosymbionts Reveals New Aspects of the
RT   Trypanosomatidae Family.";
RL   PLoS ONE 8:E60209-E60209(2013).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EPY36107.1}.
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DR   EMBL; ATMG01007076; EPY36107.1; -; Genomic_DNA.
DR   EnsemblProtists; EPY36107; EPY36107; AGDE_07079.
DR   Proteomes; UP000015341; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000015341};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015341};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    144    167       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    188    206       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    277    298       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    305    329       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    371    393       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    516    540       Helical. {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   578 AA;  64945 MW;  28B374544D57ADB1 CRC64;
     MRPTDGAVQT LQDLKEAIDG VRRRKESYFL DWYQKHRIYK VCLAMEKAVL NSMNSCTFSG
     ATCTASVWIA AKYEPALEQA LLSAVASSGE VHSVITRSDP CKNPPTYFET NKFTSSFQSI
     VDSYGMARYK EVNPGVFTII TFPYLFGIMY GDIGHGVLLL LITLYFISKE RTWKASQLNE
     MVAMVFQGRY LLLLMSLFAI YMGFLYNDFF GFSVNIFPSG YTWASLEDVN LTVTQPIIPD
     GKPSVKPSHV YAFGMDSSWA ETENKLEFYN SVKMKCAVIV GVVQMFAGII LSLCNHIYRR
     DWFRIAFLTV PEFIFLLCTF GYMSILIIVK WCTTWTDTSE APSLLEIMTN FFLQPGNVPK
     NLFRGQAGLQ VFLLIMAFLM VPIMLCGMPI IEYKKYRKHL ARMAVLQPSD TFAEQATQSE
     QVIISSSDDG EDVFGDGADI IAEPSAHDDS EEYGENFDFS EVVIHYLIHT IEYVLSSVSN
     TASYLRLWAL SLAHAQLSEV FFTFTIVNVL SADTSGALIA LGVLVWLAVT LAVLVGMEAL
     SAFLHALRLH WVEFQNKFYA GDGVGLEPFD LTSLDGRM
//
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