ID S9V0P2_9TRYP Unreviewed; 549 AA.
AC S9V0P2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Phosphatidylinositol-bisphosphatase {ECO:0000313|EMBL:EPY34573.1};
GN ORFNames=STCU_01518 {ECO:0000313|EMBL:EPY34573.1};
OS Strigomonas culicis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Strigomonadinae; Strigomonas.
OX NCBI_TaxID=28005 {ECO:0000313|EMBL:EPY34573.1, ECO:0000313|Proteomes:UP000015354};
RN [1] {ECO:0000313|EMBL:EPY34573.1, ECO:0000313|Proteomes:UP000015354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23560078;
RA Motta M.C., Martins A.C., de Souza S.S., Catta-Preta C.M., Silva R.,
RA Klein C.C., de Almeida L.G., de Lima Cunha O., Ciapina L.P., Brocchi M.,
RA Colabardini A.C., de Araujo Lima B., Machado C.R., de Almeida Soares C.M.,
RA Probst C.M., de Menezes C.B., Thompson C.E., Bartholomeu D.C., Gradia D.F.,
RA Pavoni D.P., Grisard E.C., Fantinatti-Garboggini F., Marchini F.K.,
RA Rodrigues-Luiz G.F., Wagner G., Goldman G.H., Fietto J.L., Elias M.C.,
RA Goldman M.H., Sagot M.F., Pereira M., Stoco P.H., de Mendonca-Neto R.P.,
RA Teixeira S.M., Maciel T.E., de Oliveira Mendes T.A., Urmenyi T.P.,
RA de Souza W., Schenkman S., de Vasconcelos A.T.;
RT "Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their
RT Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae
RT Family.";
RL PLoS ONE 8:E60209-E60209(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPY34573.1}.
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DR EMBL; ATMH01001518; EPY34573.1; -; Genomic_DNA.
DR AlphaFoldDB; S9V0P2; -.
DR EnsemblProtists; EPY34573; EPY34573; STCU_01518.
DR OrthoDB; 21647at2759; -.
DR Proteomes; UP000015354; Unassembled WGS sequence.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR046985; IP5.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR PANTHER; PTHR11200:SF292; PHOSPHATASE, PUTATIVE-RELATED; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015354}.
FT DOMAIN 344..548
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 549 AA; 61152 MW; C98DBBE6BB8CC972 CRC64;
MDFNASRRAE VQATANAGIV PEMLYPELFP RDHDFILVAG DLNYRLNLSY EEAVSQTQRG
ELGELLRHDQ LATELKNPHT PWKGFLALTP NHVPTYRFDI GTDTYDTSEK HRVPSFTDRI
CIWAKRPAAL RRVCVDEHVA LMRVRSSDHK PVRALLRLPI QVEVPEEKEK VLASLRQKVA
GLGLDRAASS KVSLDATLLD FGQLQFHQCG EVRTVVLTNT GDSVAVVRVL RQKPQQNEAE
DGAWTRVSPL EFAVLPGESQ EVRIETAIDP RCMGWLSRWR PYKGNGRVAI SAMLLFAVRN
GPVQAVDCRA VLLPSVFANS LENISMLGAL PCMAAYQAKM DDKTLLQSLR PQIPKELWYL
ADAVQRQPLM KDLFAATLDV DSDVCHAIMA HLDTTAAPLP AEGEPGSFNV YCVCECVLAF
LKNLQEPVVP YSMYTQALAA GRAKGKAPLA FIAQLPNAHA NVWIYMVSLL NYLLRPAHVQ
HNRLTPSLLA YVFSAAMIVR PVADQGLTSA RLLQGGGVDQ QVRQQLHQER EDAKDLVEYF
LTAAPTYMQ
//
