ID S9V750_9TRYP Unreviewed; 702 AA.
AC S9V750;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE SubName: Full=Flavoprotein subunit-like protein {ECO:0000313|EMBL:EPY36628.1};
GN ORFNames=STCU_00486 {ECO:0000313|EMBL:EPY36628.1};
OS Strigomonas culicis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Strigomonadinae; Strigomonas.
OX NCBI_TaxID=28005 {ECO:0000313|EMBL:EPY36628.1, ECO:0000313|Proteomes:UP000015354};
RN [1] {ECO:0000313|EMBL:EPY36628.1, ECO:0000313|Proteomes:UP000015354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23560078;
RA Motta M.C., Martins A.C., de Souza S.S., Catta-Preta C.M., Silva R.,
RA Klein C.C., de Almeida L.G., de Lima Cunha O., Ciapina L.P., Brocchi M.,
RA Colabardini A.C., de Araujo Lima B., Machado C.R., de Almeida Soares C.M.,
RA Probst C.M., de Menezes C.B., Thompson C.E., Bartholomeu D.C., Gradia D.F.,
RA Pavoni D.P., Grisard E.C., Fantinatti-Garboggini F., Marchini F.K.,
RA Rodrigues-Luiz G.F., Wagner G., Goldman G.H., Fietto J.L., Elias M.C.,
RA Goldman M.H., Sagot M.F., Pereira M., Stoco P.H., de Mendonca-Neto R.P.,
RA Teixeira S.M., Maciel T.E., de Oliveira Mendes T.A., Urmenyi T.P.,
RA de Souza W., Schenkman S., de Vasconcelos A.T.;
RT "Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their
RT Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae
RT Family.";
RL PLoS ONE 8:E60209-E60209(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPY36628.1}.
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DR EMBL; ATMH01000486; EPY36628.1; -; Genomic_DNA.
DR AlphaFoldDB; S9V750; -.
DR EnsemblProtists; EPY36628; EPY36628; STCU_00486.
DR OrthoDB; 1605658at2759; -.
DR Proteomes; UP000015354; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR018506; Cyt_B5_heme-BS.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR PANTHER; PTHR43400:SF1; FUMARATE REDUCTASE; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PRINTS; PR00363; CYTOCHROMEB5.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR PROSITE; PS00191; CYTOCHROME_B5_1; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000015354}.
FT DOMAIN 625..701
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
SQ SEQUENCE 702 AA; 72833 MW; 8BC1C0529FF79D63 CRC64;
MTDLDATAGG NRVIVIGGGL AGVCAAHSAL QHGASVLLLD KSAFLGGNST KASSGIAGTP
TQAQISAGVL DGVELFIKDT NRSFHGVNAT TTVGAAADTA ALPVSPLVAE MARLSGPSLD
WLVKYFNCDL SVLGFMGGHS QPRTHRGKAK MPGMAITYAL INALEAEQKK NADRARIVTR
ARVVRLIRDS ADAAAPVTGV VYADKDGKQH VARGAVVIAT GGYAADFADA SGPSTTSLIA
RFTPQLSRFA TTNGAHATGD GIKMAEQVGA GLVDMQYVQV HPSGLVDPKD PGNHIKFLCA
EATRGAGGIV VDQHGERFVD ELGRRDQVSH AMLQRQARAP FYLVLNEQSA KEMDHHCKHY
EGRGLMTRYP SITAFCEAAK VPREALARTL QQYQRDAVAN AASRGGSGGR GFFAGLFGGG
RKAPAAAAAA TLNNKGTPDA YGKTLFRNAA HFDMGRPVYV AQIAPVVHYT MGGIRVNAKT
EVLGAAAEKE ERIPGLYCAG EAAGGVHGKN RLGGNSLLDC VVYGRVAGTE AARYLLDTYL
GPFSSHRLNV IYTQLQLEEL PAVPPVPTTD VAALEAATKA ADATPAAPTP AAVAAPAAAA
AAAAPAAAAA AAPAAAPAAA DGQALRKISR AEVAKHKTEK DCWCIVHGQV LDLTAFLPDH
PGGKQSILIY GGKDATKEFD LVHQVEVIEK YTPEAVIGVV AD
//
